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Douglas A. Steeber
Researcher at University of Wisconsin–Milwaukee
Publications - 15
Citations - 2713
Douglas A. Steeber is an academic researcher from University of Wisconsin–Milwaukee. The author has contributed to research in topics: Drug delivery & Micelle. The author has an hindex of 14, co-authored 15 publications receiving 2562 citations.
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cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging
Xiaoqiang Yang,Hao Hong,Jamison J. Grailer,Ian J. Rowland,Alireza Javadi,Samuel A. Hurley,Yuling Xiao,Yunan Yang,Yin Zhang,Robert J. Nickles,Weibo Cai,Douglas A. Steeber,Shaoqin Gong +12 more
TL;DR: These SPIO nanocarriers demonstrated promising properties for combined targeted anticancer drug delivery and PET/MRI dual-modality imaging of tumors with integrin α(v)β₃ expression.
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Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery
TL;DR: Results suggest that H40-P(LA-DOX)-b-PEG-OH/FA micelles could be a promising nanocarrier with excellent in vivo stability for targeting the drugs to cancer cells and releasing the drug molecules inside the cells by sensing the acidic environment of the endosomal compartments.
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Folate-conjugated amphiphilic hyperbranched block copolymers based on Boltorn H40, poly(L-lactide) and poly(ethylene glycol) for tumor-targeted drug delivery.
TL;DR: In vitro degradation studies revealed that the H40-PLA-b-MPEG/PEG-FA block copolymer hydrolytically degraded into polymer fragments within six weeks indicated that the micelles prepared from this block polymer have great potential as tumor-targeted drug delivery nanocarriers.
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Multifunctional stable and pH-responsive polymer vesicles formed by heterofunctional triblock copolymer for targeted anticancer drug delivery and ultrasensitive MR imaging.
Xiaoqiang Yang,Jamison J. Grailer,Ian J. Rowland,Alireza Javadi,Samuel A. Hurley,Vyara Z. Matson,Douglas A. Steeber,Shaoqin Gong +7 more
TL;DR: These tumor-targeting multifunctional SPIO/DOX-loaded vesicles will provide excellent in vivo stability, pH-controlled drug release, as well as enhanced MRI contrast, thereby making targeted cancer therapy and diagnosis possible.
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Gold nanoparticles with a monolayer of doxorubicin-conjugated amphiphilic block copolymer for tumor-targeted drug delivery.
TL;DR: Results suggest that Au-P(LA-DOX)-b-PEG-OH/FA NPs could be used as a carrier with pH-triggered drug releasing properties for tumor-targeted drug delivery.