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Douglas C. Smith
Researcher at Southern Illinois University Carbondale
Publications - 25
Citations - 2591
Douglas C. Smith is an academic researcher from Southern Illinois University Carbondale. The author has contributed to research in topics: Vagus nerve stimulation & Vagus nerve. The author has an hindex of 18, co-authored 25 publications receiving 2369 citations. Previous affiliations of Douglas C. Smith include Southern Illinois University School of Medicine.
Papers
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Journal ArticleDOI
Enhanced recognition memory following vagus nerve stimulation in human subjects.
TL;DR: This work examined word-recognition memory in patients enrolled in a clinical study evaluating the capacity of vagus nerve stimulation to control epilepsy and found Stimulation administered after learning significantly enhanced retention.
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Locus Coeruleus Lesions Suppress the Seizure-Attenuating Effects of Vagus Nerve Stimulation
TL;DR: VNS is now marketed throughout most of the world as a treatment for drug‐resistant epilepsy, but the therapeutic mechanism of action of VNS‐induced seizure suppression has not yet been established and elucidation of this mechanism is an important first step in the developed strategies to improve VNS efficacy.
Journal ArticleDOI
Increased extracellular concentrations of norepinephrine in cortex and hippocampus following vagus nerve stimulation in the rat
Rodney W. Roosevelt,Douglas C. Smith,Douglas C. Smith,Richard W. Clough,Robert A. Jensen,Ronald A. Browning +5 more
TL;DR: The hypothesis that left vagus nerve stimulation (VNS) at the cervical level results in increased extracellular NE concentrations in the cortex and hippocampus was tested and these findings support the hypothesis that VNS increases extrace Cellular norepinephrine concentrations in both the hippocampus and cortex.
Journal ArticleDOI
Posttraining Electrical Stimulation of Vagal Afferents with Concomitant Vagal Efferent Inactivation Enhances Memory Storage Processes in the Rat
Kevin B. Clark,Douglas C. Smith,D.L. Hassert,Ronald A. Browning,Dean K. Naritoku,Robert A. Jensen +5 more
TL;DR: It is suggested that vagal afferents carry messages about peripheral states that lead to the modulation of memory storage and that the memory-enhancing effect produced by vagus nerve stimulation is not mediated via the activation of vagal efferents.
Patent
Methods of treating traumatic brain injury by vagus nerve stimulation
Dean K. Naritoku,Robert A. Jensen,Ronald A. Browning,Kevin B. Clark,Douglas C. Smith,Reese S. Terry +5 more
TL;DR: In this article, methods of modulating brain neural plasticity, improving memory and learning, improving recovery from traumatic brain injury, preventing epilepsy, treating memory disorders and chronic memory impairment, and treating persistent impairment of consciousness in humans and animals by vagus nerve stimulation are provided.