Douglas J. Creedon

TL;DR: In this article, a review summarizes the similarities between growth and immune privilege in cancer and pregnancy and identifies areas for further investigation, and the knowledge gained from analyzing similarities and differences between the physiologic state of pregnancy and the pathology of cancer could lead to identification of new potential targets for cancer therapeutic agents.

TL;DR: The microbiome sequencing revealed that the microbiomes of all organs (vagina, cervix, Fallopian tubes, and ovaries) are significantly correlated and that there is a structural microbiome shift in the cancer and hyperplasia cases, distinguishable from the benign cases.

TL;DR: Normal pregnancy is characterized by a microbiome that has low diversity and high stability, and comparative analyses showed that the vaginal microbiome during pregnancy is characterize by a marked dominance of Lactobacillus species in both Caucasian and African-American subjects.

TL;DR: Population-derived rates and predictors of treatment outcomes after global endometrial ablation may help physicians offer optimal preprocedural patient counseling.

TL;DR: A multi-omic, systems-biology approach including both deep 16S rRNA gene-based sequencing and metabolomics of lavage samples from 36 women revealed two distinct symptomatic BV types with similar characteristics that indicated disruption of epithelial integrity, but each type was correlated to the presence of different microbial taxa and metabolites.