D
Drew Scoles
Researcher at University of Pennsylvania
Publications - 35
Citations - 1051
Drew Scoles is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Retina & Medicine. The author has an hindex of 12, co-authored 29 publications receiving 913 citations. Previous affiliations of Drew Scoles include Medical College of Wisconsin & University of Rochester Medical Center.
Papers
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Journal ArticleDOI
In vivo imaging of human cone photoreceptor inner segments.
Drew Scoles,Yusufu N. Sulai,Christopher S Langlo,Gerald A. Fishman,Christine A. Curcio,Joseph Carroll,Alfredo Dubra +6 more
TL;DR: The application of nonconfocal split-detector to emerging human gene therapy trials will improve the potential of therapeutic success, by identifying patients with sufficient retained photoreceptor structure to benefit the most from intervention.
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In vivo dark-field imaging of the retinal pigment epithelium cell mosaic.
TL;DR: The demonstrated implementation of dark-field AOSLO imaging using 790 nm light requires low light exposures relative to light safety standards and it is more comfortable for the subject than the traditional autofluorescence RPE imaging with visible light, which makes RPE dark- field imaging appealing for studying mechanisms of eye disease.
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In-vivo imaging of retinal nerve fiber layer vasculature: imaging - histology comparison
Drew Scoles,Daniel C. Gray,Jennifer J. Hunter,Robert Wolfe,Bernard P. Gee,Ying Geng,Benjamin Masella,Richard T. Libby,Stephen R. Russell,David R. Williams,William H. Merigan +10 more
TL;DR: In-vivo, high-resolution, confocal imaging of the vasculature through the full thickness of the NFL in the living macaque, in precise agreement with histology is demonstrated.
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Adaptive Optics Retinal Imaging – Clinical Opportunities and Challenges
TL;DR: This review will briefly summarize the current state of AO retinal imaging, discuss current as well as future clinical applications of A ophthalmic adaptive optics, and provide some discussion of research needs to facilitate more widespread clinical use.
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Visualization of retinal vascular structure and perfusion with a nonconfocal adaptive optics scanning light ophthalmoscope.
TL;DR: The noninvasive visualization of capillary flow and structure provided by AOSLO split-detection shows great promise for studying ocular and systemic conditions that affect the retinal vasculature.