Duncan J. Hodkinson

TL;DR: It is demonstrated that time of the day is important when interpreting resting-state data for the purposes of using fMRI as a tool to measure changes in disease processes or in response to treatment.

TL;DR: Human imaging data are presented that strongly support the presence of abnormal low-frequency oscillations in thalamocortical networks of patients in the interictal phase of migraine, and the main source of arrhythmic activity was localized to the higher-order thalamic relays of the medial dorsal nucleus.

TL;DR: Functional magnetic resonance imaging is used to assess neural activation in migraineurs interictaly in response to emotional visual stimuli from the International Affective Picture System and supports the notion that migraine may feature more generalized altered cerebral processing of aversive/negative stimuli, rather than exclusively to sensory stimuli.

TL;DR: The analyses indicate that the pCASL imaging technique has considerable potential for the comparison of within- and between-subjects differences associated with pain-induced state changes and baseline differences in regional CBF, and suggest that differences in baseline perfusion and functional lateralisation characteristics may play an important role in the overall reliability of the estimated changes in CBF.

TL;DR: The results demonstrate the presence of a disease-specific functional deficit in a known region of the trigemino-cortical pathway, which may be driven by adaptive or maladaptive functional plasticity, and may in part explain the altered sensory experiences reported between migraine attacks.