E. N. H. Jansen

TL;DR: This work identified progressive disabling mental impairment progressing to dementia as the central feature of DLB, and identified optimal staining methods for each of these and devised a protocol for the evaluation of cortical LB frequency based on a brain sampling procedure consistent with CERAD.

TL;DR: Presently available data support the view that the occurrence of additional lesions in the form of AD stage III (or more) destruction is the most common cause of intellectual decline in PD.

TL;DR: The specific lesional pattern seen in PD destroys part of the nuclear gray matter and its connections and, thus, may likely contribute to the development of behavioral changes and autonomic dysfunction.

TL;DR: Data is reviewed on the internal organization, neuronal types, and interconnections of limbic and motor components of the human brain, and the specific lesions which a few of them undergo during the course of Parkinson's disease (neuronal loss associated with the development of Lewy bodies and Lewy neurites).

TL;DR: In Alzheimer's disease, six developmental stages can be distinguished, reflecting the predictable manner in which the neurofibrillary changes spread through the telencephalic cortex, and in Parkinson's disease lesions also impair portions of the limbic system.