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Niall Quinn

Researcher at UCL Institute of Neurology

Publications -  370
Citations -  42651

Niall Quinn is an academic researcher from UCL Institute of Neurology. The author has contributed to research in topics: Parkinson's disease & Dystonia. The author has an hindex of 95, co-authored 367 publications receiving 39775 citations. Previous affiliations of Niall Quinn include University College London.

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Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB) Report of the consortium on DLB international workshop

TL;DR: This work identified progressive disabling mental impairment progressing to dementia as the central feature of DLB, and identified optimal staining methods for each of these and devised a protocol for the evaluation of cortical LB frequency based on a brain sampling procedure consistent with CERAD.
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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.

TL;DR: Two subjects with Parkinson's disease who had long-term survival of transplanted fetal mesencephalic dopaminergic neurons (11–16 years) developed α-synuclein–positive Lewy bodies in grafted neurons, providing the first evidence, to the authors' knowledge, that the disease can propagate from host to graft cells.
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What contributes to quality of life in patients with Parkinson's disease?

TL;DR: Depression, disability, postural instability, and cognitive impairment have the greatest influence on QoL in Parkinson's disease, and the improvement of these features should become an important target in the treatment of the disease.