E
Ed Bakker
Researcher at University of Amsterdam
Publications - 6
Citations - 401
Ed Bakker is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Hepatitis & Hepatitis C virus. The author has an hindex of 3, co-authored 5 publications receiving 395 citations.
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Journal ArticleDOI
Infectivity of blood seropositive for hepatitis C virus antibodies
C. L. Van Der Poel,Hendrik W. Reesink,W. Schaasberg,Ed Bakker,P.J. Exel-Oehlers,P. N. Lelie,A. Leentvaar-Kuypers +6 more
TL;DR: Use of anti-HCV screening to prevent post-transfusion NANBH was compared with measurement of alanine aminotransferase concentrations: a corrected efficacy of 63% and 65%, a specificity of 93% and 64%, and a positive predictive value of 16.6% were found.
Journal ArticleDOI
Patterns of serological markers in transfusion-transmitted hepatitis C virus infection using second-generation HCV assays.
P. Nico Lelie,H. Theo M. Cuypers,Henk W. Reesink,Cees L. van der Poel,Irene Winkel,Ed Bakker,Patricia J. van Exel-Oehlers,David S. Vallari,Jean-Pierre Allain,Larry Minims +9 more
TL;DR: It is concluded that combined application of anti‐HCV immunoblot techniques and cDNA‐PCR in consecutive samples is necessary for reliable diagnosis of either ongoing productive or resolving HCV infection.
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Prevalence of Anti‐HCV Antibodies Confirmed by Recombinant Immunoblot in Different Population Subsets in The Netherlands
C. L. Van Der Poel,H. W. Reesink,Evelien P. Mauser-Bunschoten,R H Kaufmann,A. Leentvaar-Kuypers,R. A. F. M. Chamuleau,W. Schaasberg,Ed Bakker,P.J. Exel-Oehlers,I. Theobalds +9 more
TL;DR: In the Netherlands, HCV antibodies are low endemic among blood donors, as well as amongBlood donors from Surinam, and are more frequently observed in patients with NANBH and individuals at risk of blood‐borne virus infections.
Journal ArticleDOI
Hepatitis B core related antigen in relation to intrahepatic and circulating viral markers, before and after combination therapy.
Robin Erken,Hans L. Zaaijer,S.B. Willemse,Ed Bakker,Bart B. Takkenberg,Henk W. Reesink,Neeltje A. Kootstra +6 more
TL;DR: In this article, the relationship between hepatitis B core-related antigen (HBcrAg) and other intrahepatic and circulating viral markers in CHB patients with high viral load, before and after combination treatment was validated.
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Lack of immune potentiation by complexing HBsAg in a heat-inactivated hepatitis B vaccine with antibody in hepatitis B immunoglobulin.
P. Nico Lelie,Peter J. A. J. van Amelsfoort,C. S. Martine de Groot,Ed Bakker,W. Schaasberg,Jos C. M. Niessen,Henk W. Reesink +6 more
TL;DR: Results indicate that, in man, using a heat‐inactivated plasma vaccine, addition of anti‐HBs contained in hepatitis B immunoglobulin does not potentiate the immunogenicity of HBsAg.