E
Edith Bigot
Publications - 10
Citations - 75
Edith Bigot is an academic researcher. The author has contributed to research in topics: Reactive oxygen species & Oxidative stress. The author has an hindex of 6, co-authored 10 publications receiving 60 citations.
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Journal ArticleDOI
O-GlcNAc stimulation: A new metabolic approach to treat septic shock.
Marine Ferron,Julien Cadiet,A. Persello,Valentine Prat,M. Denis,Angélique Erraud,Virginie Aillerie,Mathieu Mével,Edith Bigot,John C. Chatham,C. Gauthier,Bertrand Rozec,Benjamin Lauzier +12 more
TL;DR: It is demonstrated that in septic shock O-GlcNAc stimulation improves global animal and cardiovascular function outcomes associated with a restoration of SERCA2a levels.
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Secondary oxidants in human serum exposed to singlet oxygen: the influence of hemolysis
TL;DR: Deactivation capability of secondary oxidants after exposure to (1)O(2) was stable over a long period of time, slightly different between men and women, but standard biochemistry parameters had little influence.
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Secondary reactive oxygen species production after PDT during pulmonary tumor growth in sera of nude mice.
TL;DR: A relationship between the general health status of an individual, cancer progression and serum capability to generate SOS during PDT is demonstrated and could explain some PDT failures as well as some unexpected successes on large tumors and should be taken into account when determining treatment parameters.
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Increased singlet oxygen-induced secondary ROS production in the serum of cancer patients.
TL;DR: Serum (1)O(2) deactivation capacity was impaired and secondary ROS were more produced during cancer progression, which would support the interest of PDT as an adjuvant for cancer treatment, even for aggressive tumors particularly when associated to surgery for bulk removal.
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Evidence for antioxidants consumption in the coronary blood of patients with an acute myocardial infarction
TL;DR: Results show that oxidants secondary to 1O2 are increased in occluded vessels during AMI in parallel to c-troponin, demonstrating that antioxidants are consumed.