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Edith Puchelle

Researcher at French Institute of Health and Medical Research

Publications -  160
Citations -  6290

Edith Puchelle is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Respiratory epithelium & Epithelium. The author has an hindex of 43, co-authored 160 publications receiving 6042 citations. Previous affiliations of Edith Puchelle include University of Reims Champagne-Ardenne & Hochschule Hannover.

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Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary disease.

TL;DR: In vitro and in vivo models of airway epithelial wound repair and regeneration allow the study of the spatiotemporal modulation of cellular and molecular interaction factors-namely, the proinflammatory cytokines, the matrix metalloproteinases and their inhibitors, and the intercellular adhesion molecules.
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ΔF508 CFTR protein expression in tissues from patients with cystic fibrosis

TL;DR: The tissue-specific variation of ΔF508 CFTR expression from null to apparently normal amounts indicates that ΔF50 CFTR maturation can be modulated and suggests that determinants other than CFTR mislocalization should play a role in Δf508 CF respiratory and intestinal disease.
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Cell Migration and Proliferation During the In Vitro Wound Repair of the Respiratory Epithelium

TL;DR: It is demonstrated that cell proliferation and cell migration during respiratory epithelial wound repair are differently expressed with regard to the cell location within the repairing area.
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Adherence of type I Streptococcus pneumoniae to tracheal epithelium of mice infected with influenza A/PR8 virus.

TL;DR: Pneumococci were observed adhered to the microvilli of the basal cells and, to a greater extent, to the exposed basement membrane, while mice infected with PR8/A influenza virus were never seen attached to control tracheas.
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Embryonic stem cells generate airway epithelial tissue.

TL;DR: It is shown by RT-PCR and immunocytochemistry that murine ES cells are able to differentiate into nonciliated secretory Clara cells, and that type I collagen induces this commitment, and when cultured at the air-liquid interface, ES cells give rise to a fully differentiated airway epithelium.