D
Dominique Gaillard
Researcher at French Institute of Health and Medical Research
Publications - 85
Citations - 4582
Dominique Gaillard is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Cystic fibrosis & Epithelium. The author has an hindex of 37, co-authored 85 publications receiving 4147 citations. Previous affiliations of Dominique Gaillard include University of Reims Champagne-Ardenne.
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Journal ArticleDOI
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus
Sébastien Jacquemont,Alexandre Reymond,Flore Zufferey,Louise Harewood,Robin G. Walters,Zoltán Kutalik,Danielle Martinet,Yiping Shen,Armand Valsesia,Armand Valsesia,Noam D. Beckmann,Gudmar Thorleifsson,Marco Belfiore,Sonia Bouquillon,Dominique Campion,Nicole de Leeuw,Bert B.A. de Vries,Tõnu Esko,Bridget A. Fernandez,Fernando Fernández-Aranda,José Manuel Fernández-Real,Mònica Gratacòs,Audrey Guilmatre,Juliane Hoyer,Marjo-Riitta Järvelin,R. Frank Kooy,Ants Kurg,Cédric Le Caignec,Katrin Männik,Orah S. Platt,Damien Sanlaville,Mieke M. van Haelst,Sergi Villatoro Gomez,Faida Walha,Bai-Lin Wu,Yongguo Yu,Azzedine Aboura,Marie-Claude Addor,Yves Alembik,Stylianos E. Antonarakis,Benoit Arveiler,Magalie Barth,Nathalie Bednarek,Frédérique Béna,Sven Bergmann,Mylène Beri,Laura Bernardini,Bettina Blaumeiser,Dominique Bonneau,Armand Bottani,Odile Boute,Han G. Brunner,Dorothée Cailley,Patrick Callier,Jean Chiesa,Jacqueline Chrast,Lachlan J. M. Coin,Charles Coutton,Jean-Marie Cuisset,Jean-Christophe Cuvellier,Albert David,Bénédicte de Fréminville,Bruno Delobel,Marie-Ange Delrue,Bénédicte Demeer,Dominique Descamps,Gérard Didelot,Klaus Dieterich,Vittoria Disciglio,Martine Doco-Fenzy,Séverine Drunat,Bénédicte Duban-Bedu,Christèle Dubourg,Julia S. El-Sayed Moustafa,Paul Elliott,Brigitte H. W. Faas,Laurence Faivre,Anne Faudet,Florence Fellmann,Alessandra Ferrarini,Richard I. Fisher,Elisabeth Flori,Lukas Forer,Dominique Gaillard,Marion Gérard,Christian Gieger,Stefania Gimelli,Giorgio Gimelli,Hans J. Grabe,Agnès Guichet,Olivier Guillin,Anna-Liisa Hartikainen,Delphine Héron,Loyse Hippolyte,Muriel Holder,Georg Homuth,Bertrand Isidor,Sylvie Jaillard,Zdenek Jaros,Susana Jiménez-Murcia,Geraldine Joly Helas,Philippe Jonveaux,Satu Kaksonen,Boris Keren,Anita Kloss-Brandstätter,Nine V A M Knoers,David A. Koolen,Peter M. Kroisel,Florian Kronenberg,Audrey Labalme,Emilie Landais,Elisabetta Lapi,Valérie Layet,Solenn Legallic,Bruno Leheup,Barbara Leube,Suzanne M E Lewis,Josette Lucas,Kay D. MacDermot,Páll Magnússon,Christian R. Marshall,Michèle Mathieu-Dramard,Mark I. McCarthy,Mark I. McCarthy,Thomas Meitinger,Maria Antonietta Mencarelli,Giuseppe Merla,Alexandre Moerman,Vincent Mooser,Fanny Morice-Picard,Mafalda Mucciolo,Matthias Nauck,Ndeye Coumba Ndiaye,Ann Nordgren,Laurent Pasquier,Florence Petit,Rolph Pfundt,Ghislaine Plessis,Evica Rajcan-Separovic,Gian Paolo Ramelli,Anita Rauch,Roberto Ravazzolo,André Reis,Alessandra Renieri,Cristóbal Richart,Janina S. Ried,Claudine Rieubland,Wendy Roberts,Katharina M. Roetzer,Caroline Rooryck,Massimiliano Rossi,Evald Saemundsen,Véronique Satre,Claudia Schurmann,Engilbert Sigurdsson,Dimitri J. Stavropoulos,Hreinn Stefansson,Carola Tengstrom,Unnur Thorsteinsdottir,Francisco J. Tinahones,R. Touraine,Louis Vallée,Ellen van Binsbergen,Nathalie Van der Aa,Catherine Vincent-Delorme,Sophie Visvikis-Siest,Peter Vollenweider,Henry Völzke,Anneke T. Vulto-van Silfhout,Gérard Waeber,Carina Wallgren-Pettersson,Robert M. Witwicki,Simon Zwolinksi,Joris Andrieux,Xavier Estivill,James F. Gusella,Omar Gustafsson,Andres Metspalu,Stephen W. Scherer,Kari Stefansson,Alexandra I. F. Blakemore,Jacques S. Beckmann,Philippe Froguel +182 more
TL;DR: In this article, the reciprocal duplication is associated with being clinically underweight, which is the main sign of a series of heterogeneous clinical conditions including failure to thrive, feeding and eating disorder and/or anorexia nervosa.
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus
Sébastien Jacquemont,Alexandre Reymond,Flore Zufferey,Louise Harewood,Robin G. Walters,Zoltán Kutalik,Danielle Martinet,Yiping Shen,Armand Valsesia,Noam D. Beckmann,Gudmar Thorleifsson,Marco Belfiore,Sonia Bouquillon,Dominique Campion,Nicole de Leeuw,Bert B.A. de Vries,Tõnu Esko,Bridget A. Fernandez,Fernando Fernández-Aranda,José Manuel Fernández-Real,Mònica Gratacòs,Audrey Guilmatre,Juliane Hoyer,Marjo-Riitta Järvelin,R. Frank Kooy,Ants Kurg,Cédric Le Caignec,Katrin Maennik,Orah S. Platt,Damien Sanlaville,Mieke M. van Haelst,Sergi Villatoro Gomez,Faida Walha,Bai-Lin Wu,Yongguo Yu,Azzedine Aboura,Marie-Claude Addor,Yves Alembik,Stylianos E. Antonarakis,Benoit Arveiler,Magalie Barth,Nathalie Bednarek,Frédérique Béna,Sven Bergmann,Mylène Beri,Laura Bernardini,Bettina Blaumeiser,Dominique Bonneau,Armand Bottani,Odile Boute,Han G. Brunner,Dorothée Cailley,Patrick Callier,Jean Chiesa,Jacqueline Chrast,Lachlan J. M. Coin,Charles Coutton,Jean-Marie Cuisset,Jean-Christophe Cuvellier,Albert David,Bénédicte de Fréminville,Bruno Delobel,Marie-Ange Delrue,Bénédicte Demeer,Dominique Descamps,Gérard Didelot,Klaus Dieterich,Vittoria Disciglio,Martine Doco-Fenzy,Séverine Drunat,Bénédicte Duban-Bedu,Christèle Dubourg,Julia S. El-Sayed Moustafa,Paul Elliott,Brigitte H. W. Faas,Laurence Faivre,Anne Faudet,Florence Fellmann,Alessandra Ferrarini,Richard I. Fisher,Elisabeth Flori,Lukas Forer,Dominique Gaillard,Marion Gérard,Christian Gieger,Stefania Gimelli,Giorgio Gimelli,Hans J. Grabe,Agnès Guichet,Olivier Guillin,Anna-Liisa Hartikainen,Delphine Héron,Loyse Hippolyte,Muriel Holder,Georg Homuth,Bertrand Isidor,Sylvie Jaillard,Zdenek Jaros,Susana Jiménez-Murcia,Geraldine Joly Helas,Philippe Jonveaux,Satu Kaksonen,Boris Keren,Anita Kloss-Brandstaetter,Nine V A M Knoers,David A. Koolen,Peter M. Kroisel,Florian Kronenberg,Audrey Labalme,Emilie Landais,Elisabetta Lapi,Valérie Layet,Solenn Legallic,Bruno Leheup,Barbara Leube,Suzanne M E Lewis,Josette Lucas,Kay D. MacDermot,Páll Magnússon,Christian R. Marshall,Michèle Mathieu-Dramard,Mark I. McCarthy,Thomas Meitinger,Maria Antonietta Mencarelli,Giuseppe Merla,Alexandre Moerman,Vincent Mooser,Fanny Morice-Picard,Mafalda Mucciolo,Matthias Nauck,Ndeye Coumba Ndiaye,Ann Nordgren,Laurent Pasquier,Florence Petit,Rolph Pfundt,Ghislaine Plessis,Evica Rajcan-Separovic,Gian Paolo Ramelli,Anita Rauch,Roberto Ravazzolo,André Reis,Alessandra Renieri,Cristóbal Richart,Janina S. Ried,Claudine Rieubland,Wendy Roberts,Katharina M. Roetzer,Caroline Rooryck,Massimiliano Rossi,Evald Saemundsen,Véronique Satre,Claudia Schurmann,Engilbert Sigurdsson,Dimitri J. Stavropoulos,Hreinn Stefansson,Carola Tengstrom,Unnur Thorsteinsdottir,Francisco J. Tinahones,Renaud Touraine,Louis Vallée,Ellen van Binsbergen,Nathalie Van der Aa,Catherine Vincent-Delorme,Sophie Visvikis-Siest,Peter Vollenweider,Henry Voelzke,Anneke T. Vulto-van Silfhout,Gérard Waeber,Carina Wallgren-Pettersson,Robert M. Witwicki,Simon Zwolinksi,Joris Andrieux,Xavier Estivill,James F. Gusella,Omar Gustafsson,Andres Metspalu,Stephen W. Scherer,Kari Stefansson,Alexandra I. F. Blakemore,Jacques S. Beckmann,Philippe Froguel +180 more
TL;DR: The reciprocal impact of these 16p11.2 copy-number variants indicates that severe obesity and being underweight could have mirror aetiologies, possibly through contrasting effects on energy balance.
Journal ArticleDOI
Embryonic stem cells generate airway epithelial tissue.
Christelle Coraux,Béatrice Nawrocki-Raby,Jocelyne Hinnrasky,C. Kileztky,Dominique Gaillard,Christian Dani,Edith Puchelle +6 more
TL;DR: It is shown by RT-PCR and immunocytochemistry that murine ES cells are able to differentiate into nonciliated secretory Clara cells, and that type I collagen induces this commitment, and when cultured at the air-liquid interface, ES cells give rise to a fully differentiated airway epithelium.
Journal ArticleDOI
Selective Up-Regulation of Chemokine IL-8 Expression in Cystic Fibrosis Bronchial Gland Cells in Vivo and in Vitro
Olivier Tabary,J.M. Zahm,Jocelyne Hinnrasky,Jean Paul Couetil,Pascale Cornillet,Moncef Guenounou,Dominique Gaillard,Edith Puchelle,Jacky Jacquot +8 more
TL;DR: The selective up-regulation of bronchial submucosal gland IL-8 could represent a primary event that initiates early airway sub mucosal inflammation in CF patients, and is relevant to the pathogenesis of CF.
Journal Article
Evidence for a common mechanism of action for fatty acids and thiazolidinedione antidiabetic agents on gene expression in preadipose cells.
Azeddine Ibrahimi,Lydia Teboul,Dominique Gaillard,Ez-Zoubir Amri,G. Ailhaud,P. Young,Michael A. Cawthorne,P. Grimaldi +7 more
TL;DR: It is reported that a new thiazolidinedione compound, BRL 49653, exerts potent effects on the expression of genes encoding proteins involved in fatty acid metabolism in preadipose cells, similar to those already described for natural or nonmetabolizable fatty acids.