E
Edward L. O'Connell
Researcher at Yale University
Publications - 19
Citations - 1199
Edward L. O'Connell is an academic researcher from Yale University. The author has contributed to research in topics: Isomerase & Aldolase A. The author has an hindex of 13, co-authored 19 publications receiving 1189 citations.
Papers
More filters
Journal ArticleDOI
Mechanism of Aconitase Action I. THE HYDROGEN TRANSFER REACTION
TL;DR: Five experiments that support a mechanism of base-catalyzed proton abstraction from hydroxy acid substrate and the amount of tritium found in the glutamate agrees with the prediction based on the relative initial rates of formation of isocitrate and cis-aconitate from citrate.
Journal ArticleDOI
Role of inorganic phosphate in stimulating the glucose utilization of human red blood cells
Journal ArticleDOI
Intramolecular hydrogen transfer in the phosphoglucose isomerase reaction.
Journal ArticleDOI
The role of glucose 6-phosphate in the regulation of glucose metabolism in human erythrocytes.
TL;DR: The present experiments show that the estent of increase in utilization seen in the presence of methylene blue is correlated with decreased glucose-6-P content and that there is no functional glucose 6-phosphatase in the erythrocyte, but that red cell hexokinase is inhibited by glucose-7-P to a degree consistent with the conclusion that it is the concentration of glucose- 6-P.
Journal ArticleDOI
Studies on the Interaction of Aldolase with Substrate Analogues
TL;DR: It is concluded from inactivation and labeling studies that glycolaldehyde-P can form a Schiff's base at the dihydroxyacetone-P site and that the inactivation of aldolase as a result of reaction with l-glyceraldehyde-3-P is like that produced by carboxypeptidase in that it seems to inhibit the rate of —C—H bond cleavage