E
Edward M. Gilbert
Researcher at University of Utah
Publications - 214
Citations - 21330
Edward M. Gilbert is an academic researcher from University of Utah. The author has contributed to research in topics: Heart failure & Transplantation. The author has an hindex of 55, co-authored 209 publications receiving 20647 citations. Previous affiliations of Edward M. Gilbert include Intermountain Medical Center & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure
Milton Packer,Michael R. Bristow,Jay N. Cohn,Wilson S. Colucci,Michael B. Fowler,Edward M. Gilbert,Neil H. Shusterman +6 more
TL;DR: Carvedilol reduces the risk or death as well as the risk of hospitalization for cardiovascular causes in patients with heart failure who are receiving treatment with digoxin, diuretics, and an angiotensin-converting-enzyme inhibitor.
Journal Article
The Effect of Carvedilol on Morbidity and Mortality in Patients With Chronic Heart Failure
Milton Packer,Michael R. Bristow,Jay N. Cohn,Wilson S. Colucci,Michael B. Fowler,Edward M. Gilbert,Neil H. Shusterman +6 more
TL;DR: In this paper, a double-blind, placebo-controlled, stratified program, in which patients were assigned to one of four treatment protocols on the basis of their exercise capacity, was presented.
Journal ArticleDOI
Carvedilol Produces Dose-Related Improvements in Left Ventricular Function and Survival in Subjects With Chronic Heart Failure
Michael R. Bristow,Edward M. Gilbert,William T. Abraham,Kirkwood F. Adams,Michael B. Fowler,Ray E. Hershberger,Spencer H. Kubo,Kenneth A. Narahara,Henry Ingersoll,Steven K. Krueger,Sarah Young,Neil H. Shusterman +11 more
TL;DR: In subjects with mild to moderate heart failure from systolic dysfunction, carvedilol produced dose-related improvements in LV function and dose- related reductions in mortality and hospitalization rate and was generally well tolerated.
Journal ArticleDOI
Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy
Finn Waagstein,Å Hjalmarson,Karl Swedberg,Michael R. Bristow,Edward M. Gilbert,F. Camerini,Michael B. Fowler,Marc A. Silver,M.R. Johnson,F.G. Goss +9 more
TL;DR: In patients with idiopathic dilated cardiomyopathy, treatment with metoprolol prevented clinical deterioration, improved symptoms and cardiac function, and was well tolerated.
Journal ArticleDOI
Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium.
Brian D. Lowes,Wayne Minobe,William T. Abraham,Mona N. Rizeq,Teresa J. Bohlmeyer,Robert A. Quaife,Robert L. Roden,Darrin L. Dutcher,Alastair O. Robertson,Norbert F. Voelkel,David B. Badesch,Bertron M. Groves,Edward M. Gilbert,Michael R. Bristow +13 more
TL;DR: Both nonfailing intact and explanted human ventricular myocardium expressed substantial amounts of alpha-myosin heavy chain mRNA (alpha-MHC, 23-34% of total), and it is concluded that at the mRNA level nonf failing human heart expresses substantial alpha-M HC.