E
Edward M. Lawrence
Researcher at University of Cambridge
Publications - 17
Citations - 465
Edward M. Lawrence is an academic researcher from University of Cambridge. The author has contributed to research in topics: Medicine & Prostate. The author has an hindex of 9, co-authored 12 publications receiving 382 citations. Previous affiliations of Edward M. Lawrence include Memorial Sloan Kettering Cancer Center.
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Journal ArticleDOI
Definitions of terms, processes and a minimum dataset for transperineal prostate biopsies: a standardization approach of the Ginsburg Study Group for Enhanced Prostate Diagnostics
Timur H. Kuru,Timur H. Kuru,Karan Wadhwa,Richard T. M. Chang,Lina Maria Carmona Echeverria,Matthias Roethke,Alexander Polson,Giles Rottenberg,Brendan Koo,Edward M. Lawrence,Jonas Seidenader,Vincent J. Gnanapragasam,Richard G. Axell,Wilfried Roth,Anne Y. Warren,Andrew Doble,Gordon Muir,Rick Popert,Heinz Peter Schlemmer,Boris Hadaschik,Christof Kastner +20 more
TL;DR: To define terms and processes and agree on a minimum dataset in relation to transperineal prostate biopsy procedures and enhanced prostate diagnostics and establish a collaborative research practice.
Journal ArticleDOI
Prospective study evaluating the relative sensitivity of 18F-NaF PET/CT for detecting skeletal metastases from renal cell carcinoma in comparison to multidetector CT and 99mTc-MDP bone scintigraphy, using an adaptive trial design
E. L. Gerety,Edward M. Lawrence,James Wason,H. Yan,Sarah Hilborne,J. Buscombe,H.K. Cheow,A. S. Shaw,Nick Bird,Kate Fife,Sarah Heard,David J. Lomas,David J. Lomas,Athena Matakidou,Athena Matakidou,Dmitry Soloviev,Timothy Eisen,Timothy Eisen,Ferdia A. Gallagher,Ferdia A. Gallagher +19 more
TL;DR: 18F-NaF PET/CT could alter management by identifying occult metastases in patients with negative standard-of-care imaging by showing it is more than twice assensitive as CT and more than three times as sensitive as bone scintigraphy for these lesions.
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Preoperative 3-T diffusion-weighted MRI for the qualitative and quantitative assessment of extracapsular extension in patients with intermediate- or high-risk prostate cancer.
Edward M. Lawrence,Ferdia A. Gallagher,Tristan Barrett,Anne Y. Warren,Andrew N. Priest,Debra A. Goldman,Evis Sala,Vincent J. Gnanapragasam +7 more
TL;DR: The addition of DWI and ADC mapping to T2-weighted MRI improved the accuracy of preoperative detection of ECE and may be useful in the pretreatment assessment of patients with prostate cancer.
Journal ArticleDOI
Ratio of Tumor to Normal Prostate Tissue Apparent Diffusion Coefficient as a Method for Quantifying DWI of the Prostate.
Tristan Barrett,Andrew N. Priest,Edward M. Lawrence,Debra A. Goldman,Anne Y. Warren,Vincent J. Gnanapragasam,Evis Sala,Ferdia A. Gallagher +7 more
TL;DR: The use of a simple ratio of prostate tumor ADC to normal tissue ADC improved the concordance between different b value combinations and could provide a more robust means of assessing restricted diffusion in the prostate.
Journal ArticleDOI
Prostate cancer: performance characteristics of combined T₂W and DW-MRI scoring in the setting of template transperineal re-biopsy using MR-TRUS fusion.
Edward M. Lawrence,Sarah Y. W. Tang,Tristan Barrett,Brendan Koo,Debra A. Goldman,Anne Y. Warren,Richard G. Axell,Andrew Doble,Ferdia A. Gallagher,Vincent J. Gnanapragasam,Christof Kastner,Evis Sala +11 more
TL;DR: MRI targeting is beneficial in the setting of TTP MR-TRUS fusion re-biopsy and MR suspicion score relates to prostate cancer clinical significance, and a T2W and DW-MRI structured scoring system results in good inter-reader agreement in this setting.