Sarah Hilborne

TL;DR: Imaging of hyperpolarized [1-13C]pyruvate metabolism in breast cancer is feasible and demonstrated significant intertumoral and intratumoral metabolic heterogeneity, where lactate labeling correlated with MCT1 expression and hypoxia.

TL;DR: 18F-NaF PET/CT could alter management by identifying occult metastases in patients with negative standard-of-care imaging by showing it is more than twice assensitive as CT and more than three times as sensitive as bone scintigraphy for these lesions.

TL;DR: Hyperpolarized 13C MRI enabled successful identification of breast cancer response after one cycle of neoadjuvant chemotherapy and may improve response prediction when used in conjunction with multiparametric proton MRI.

TL;DR: In this paper , the authors sequenced 482 SARS-CoV-2 isolates from the University of Cambridge from 5 October to 6 December 2020 and performed a detailed phylogenetic comparison with 972 isolate from the surrounding community, complemented with epidemiological and contact tracing data to determine transmission dynamics.

TL;DR: MRI can distinguish between acute and evolving or chronic lower limb DVT, and synergistic venous assessment with combined NC-MRV and MR-DTI is able to distinguish acute venous thrombosis from the established or evolving DVT detected by ultrasound.