E
Edward S. Cole
Researcher at Toronto General Hospital
Publications - 64
Citations - 4733
Edward S. Cole is an academic researcher from Toronto General Hospital. The author has contributed to research in topics: Transplantation & Renal function. The author has an hindex of 34, co-authored 63 publications receiving 4552 citations. Previous affiliations of Edward S. Cole include Rowan University & Genzyme.
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Journal ArticleDOI
Evolution of the absorption profile of cyclosporine A in renal transplant recipients: a longitudinal study of the de novo and maintenance phases
Matthias Büchler,Steve Chadban,Edward S. Cole,Karsten Midtvedt,Eric Thervet,Hans Prestele,Paul Keown +6 more
TL;DR: CsA clearance accelerates between months 3 and 12 post-transplant, resulting in lower C0 levels for a given exposure (as measured by C2), and C2 monitoring contributes to improved individualized CsA-ME treatment in both the de novo phase and beyond month 3.
Journal ArticleDOI
No Detrimental Effect On Renal Function During Long-term Use Of Fluvastatin
Hallvard Holdaas,Bengt Fellström,Alan G. Jardine,Gudrun Nyberg,Carola Grönhagen-Riska,Søren Madsen,Hans-Hellmut Neumayer,Edward S. Cole,Bart Maes,Anders Hartmann,Patrice M. Ambühl,Claudio Gimpelewicz,Beatrix Staffler,John Logan +13 more
TL;DR: Fluvastatin had no detrimental effect on renal function, or the risk of renal AEs, in renal transplant recipients with or without diabetes enrolled in ALERT, and may be used without fear of jeopardizing renal function.
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A comparison of the effects of C2-cyclosporine and C0-tacrolimus on renal function and cardiovascular risk factors in kidney transplant recipients.
S. Kim,Gv Ramesh Prasad,Michael Huang,Michelle M. Nash,Olusegun Famure,Joseph Park,Mary Thenganatt,Nizamuddin Chowdhury,Edward S. Cole,Stanley S. A. Fenton,Daniel C. Cattran,Jeffrey S. Zaltzman,Carl J. Cardella +12 more
TL;DR: There was a greater decline in eGFR for patients on C2-CsA between one and six months posttransplant, however, MAP, TC, and the risk of NODM were comparable in both treatment/monitoring groups.
Journal ArticleDOI
Comparison of two in vitro methods for the measurement of recombinant human TSH bioactivity.
Rebecca Sendak,Fei Wang,Laura B. Geagan,Lori A. Armstrong,Charles D. Thyne,Edward S. Cole,Robert J. Mattaliano +6 more
TL;DR: Both assay systems provide a suitable means for measuring the activity of rhTSH and the average time required to analyse a sample using the membrane-based method was more than twice as long as that needed to test a sample in the cell-based assay.
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The dual kidney transplant registry.
Edward J. Alfrey,Amy D. Lu,J.T Carter,Victor Bowers,R Taylor,Lloyd E. Ratner,Edward S. Cole,Eugene J. Schweitzer,Venkatesh Krishnamurthi,Henkie P. Tan,Robert J. Stratta +10 more
TL;DR: Reducing cold storage time may be the single most important aspect to insuring long-term graft survival in recipients of aged dual kidney transplants.