P
Paul Keown
Researcher at University of British Columbia
Publications - 197
Citations - 10613
Paul Keown is an academic researcher from University of British Columbia. The author has contributed to research in topics: Transplantation & Population. The author has an hindex of 48, co-authored 187 publications receiving 10058 citations. Previous affiliations of Paul Keown include Vancouver General Hospital & Semmelweis University.
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Journal ArticleDOI
International standardization of criteria for the histologic diagnosis of renal allograft rejection : the Banff working classification of kidney transplant pathology
Kim Solez,Roy A. Axelsen,Hallgrimur Benediktsson,James F. Burdick,Arthur H. Cohen,Robert B. Colvin,Byron P. Croker,Dominique Droz,Michael S. Dunnill,Philip F. Halloran,Pekka Häyry,J. Charles Jennette,Paul Keown,Niels Marcussen,Michael J. Mihatsch,Kunio Morozumi,Bryan D. Myers,Cynthia C. Nast,Steen Olsen,Lorraine C. Racusen,E L Ramos,Seymour Rosen,David H. Sachs,Daniel R. Salomon,Fred Sanfilippo,Regina R. Verani,Eeva von Willebrand,Yutaka Yamaguchi +27 more
TL;DR: A schema for international standardization of nomenclature and criteria for the histologic diagnosis of renal allograft rejection was developed in Banff, Canada on August 2-4, 1991 and validated by the circulation of sets of slides for scoring by participant pathologists.
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A study of the quality of life and cost-utility of renal transplantation
Andreas Laupacis,Paul Keown,Nancy Pus,Hans Krueger,Beryl Ferguson,Cynthia J. Wong,Norman Muirhead +6 more
TL;DR: It is concluded that renal transplantation was more effective and less costly than dialysis in all subgroups of patients examined, including patients older than 60 and diabetics.
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A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation
Paul Keown,Pekka Häyry,Peter J. Morris,Calvin R. Stiller,Christopher M. Barker,Lisa Carr,David Landsberg,Ian R. Hardie,Russell J. Rigby,Helena Isoniemi,Derek W. R. Gray,Philip Belitsky,Allan McDonald,Tim Mathew,A. Clarkson,L. Barratt,B. Buchholz,Rowan Walker,Günther Kirste,Norman Muirhead,David J. Tiller,Geoff Duggin,Philip F. Halloran,Pierre Daloze,Gilles St. Louis,David Russell,David Ludwin,P. Vialtel,U. Binswanger,J. A C Buckels,Jean Louis Touraine,David P. Hickey,Giuseppe Remuzzi,Giuseppe Locatelli,F. T. Lam,Ed Tapper +35 more
TL;DR: MMF is associated with a significantly lower rate of treatment failure compared with AZA during the first 6 months after renal transplantation and produces a clinically important reduction in the incidence, severity, and treatment of acute graft rejection.
Journal ArticleDOI
New onset diabetes mellitus in patients receiving calcineurin inhibitors: a systematic review and meta-analysis.
TL;DR: A meta‐analysis evaluates the reported incidence of NODM after solid organ transplantation in patients receiving CNI treatment and concludes that new onset diabetes mellitus is a serious complication of transplantation.
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Therapeutic drug monitoring of immunosuppressant drugs in clinical practice
TL;DR: Current data on TDM of the following immunosuppressant drugs used in organ transplantation are summarized, and recent findings indicate that monitoring of drug levels 2 hours after dosing is a more sensitive predictor of outcome than trough (C0) monitoring.