B
Bengt Fellström
Researcher at Uppsala University
Publications - 202
Citations - 12792
Bengt Fellström is an academic researcher from Uppsala University. The author has contributed to research in topics: Transplantation & Kidney disease. The author has an hindex of 50, co-authored 193 publications receiving 11547 citations. Previous affiliations of Bengt Fellström include Norwegian University of Science and Technology & Ludwig Institute for Cancer Research.
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Journal ArticleDOI
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
Colin Baigent,Martin J Landray,Christina Reith,Jonathan Emberson,David C. Wheeler,Charles R.V. Tomson,Christoph Wanner,Vera Krane,Alan Cass,Jonathan C. Craig,Bruce Neal,Lixin Jiang,Lai Seong Hooi,Adeera Levin,Lawrence Y. Agodoa,Mike Gaziano,Bertram L. Kasiske,Robert J. Walker,Ziad A. Massy,Bo Feldt-Rasmussen,Udom Krairittichai,Vuddidhej Ophascharoensuk,Bengt Fellström,Hallvard Holdaas,Vladimir Tesar,Andrzej Wiecek,Diederick E. Grobbee,Dick de Zeeuw,Carola Grönhagen-Riska,Tanaji Dasgupta,David Lewis,William G. Herrington,Marion Mafham,William Majoni,K Wallendszus,Richard H. Grimm,Terje R. Pedersen,Jonathan A. Tobert,Jane Armitage,Alex Baxter,Christopher Bray,Yiping Chen,Zhengming Chen,Michael Hill,Carol Knott,Sarah Parish,David Simpson,Peter Sleight,Alan Young,Rory Collins +49 more
TL;DR: Reduction of LDL cholesterol with simvastatin 20 mg plus ezetimibe 10 mg daily safely reduced the incidence of major atherosclerotic events in a wide range of patients with advanced chronic kidney disease.
Journal ArticleDOI
Rosuvastatin and cardiovascular events in patients undergoing hemodialysis
Bengt Fellström,Alan G. Jardine,Roland E. Schmieder,Hallvard Holdaas,Kym M. Bannister,J.J. Beutler,Dong Wan Chae,Alejandro Chevaile,Stuart M. Cobbe,Carola Grönhagen-Riska,José Jayme Galvão de Lima,Robert L. Lins,Gert Mayer,Alan W. McMahon,Hans-Henrik Parving,Hans-Henrik Parving,Giuseppe Remuzzi,Ola Samuelsson,Sandor Sonkodi,Gultekin Suleymanlar,Dimitrios Tsakiris,Vladimir Tesar,Vasil Todorov,Andrzej Wiecek,Rudolf P. Wüthrich,Mattis Gottlow,Eva Johnsson,Faiez Zannad +27 more
TL;DR: In patients undergoing hemodialysis, the initiation of treatment with rosuvastatin lowered the LDL cholesterol level but had no significant effect on the composite primary end point of death from cardiovascular causes, nonf fatal myocardial infarction, or nonfatal stroke.
Journal ArticleDOI
Effect of fluvastatin on cardiac outcomes in renal transplant recipients: a multicentre, randomised, placebo-controlled trial
Hallvard Holdaas,Bengt Fellström,Alan G. Jardine,Ingar Holme,Gudrun Nyberg,Per Fauchald,Carola Grönhagen-Riska,Søren Madsen,Hans-Hellmut Neumayer,Edward S. Cole,Bart Maes,Patrice M. Ambühl,Anders G. Olsson,Anders Hartmann,D. Solbu,Terje R. Pedersen +15 more
TL;DR: Overall effects of fluvastatin were similar to those of statins in other populations, and seemed to be reduced in cardiac deaths and non-fatal MI, but did not generally reduce rates of coronary intervention procedures or mortality.
Journal ArticleDOI
Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
Jane Armitage,Colin Baigent,Elizabeth H Barnes,D. John Betteridge,Lisa Blackwell,Michael A. Blazing,Louise Bowman,Eugene Braunwald,Robert P Byington,Christopher P. Cannon,Michael Clearfield,Helen M. Colhoun,Rory Collins,Björn Dahlöf,Kelly Davies,Barry R. Davis,James A. de Lemos,John R. Downs,Paul N. Durrington,Jonathan Emberson,Bengt Fellström,Marcus Flather,Ian Ford,Maria Grazia Franzosi,Jordan Fulcher,John H. Fuller,Curt D. Furberg,David L. Gordon,Shinya Goto,Antonio M. Gotto,Heather Halls,Charlie H.S. Harper,C. Morton Hawkins,William G. Herrington,Graham A. Hitman,Hallvard Holdaas,Lisa Holland,Alan G. Jardine,J. Wouter Jukema,John J.P. Kastelein,Sharon Kean,Anthony C Keech,Adrienne Kirby,John Kjekshus,Genell L. Knatterud,Robert H. Knopp,Wolfgang Koenig,Michael J. Koren,Vera Krane,Martin J Landray,John C. LaRosa,Eva Lonn,Peter W. Macfarlane,Stephen MacMahon,Aldo P. Maggioni,Roberto Marchioli,Ian C. Marschner,Borislava Mihaylova,Lemuel A. Moyé,Sabina A. Murphy,Haruo Nakamura,Andrew Neil,Connie B. Newman,Rachel O'Connell,Chris J. Packard,Sarah Parish,Terje R. Pedersen,Richard Peto,Marc A. Pfeffer,Neil Poulter,David Preiss,Christina Reith,Paul M. Ridker,Michele Robertson,Frank M. Sacks,Naveed Sattar,Roland E. Schmieder,Patrick W. Serruys,Peter S. Sever,John Shaw,Charles L. Shear,John Simes,Peter Sleight,Enti Spata,Luigi Tavazzi,Jonathan A. Tobert,Gianni Tognoni,Andrew Tonkin,Stella Trompet,John Varigos,Christoph Wanner,Hans Wedel,Harvey D. White,John Wikstrand,Lars Wilhelmsen,Kate Wilson,R. Young,Salim Yusuf,Faiez Zannad +98 more
TL;DR: A meta-analysis of data from all large statin trials to compare the effects of statin therapy at different ages observed a significant reduction in major vascular events in all age groups.
Journal ArticleDOI
Diagnostic Utility of Exome Sequencing for Kidney Disease
Emily E. Groopman,Maddalena Marasa,Sophia R. Cameron-Christie,Slavé Petrovski,Vimla Aggarwal,Hila Milo-Rasouly,Yifu Li,Junying Zhang,Jordan G. Nestor,Priya Krithivasan,Wan Yee Lam,Adele Mitrotti,Stacy Piva,Byum Hee Kil,Debanjana Chatterjee,Rachel Reingold,Drew Bradbury,Michael DiVecchia,Holly J. Snyder,Xueru Mu,Karla Mehl,Olivia Balderes,David Fasel,Chunhua Weng,Jai Radhakrishnan,Pietro A. Canetta,Gerald B. Appel,Andrew S. Bomback,Wooin Ahn,Natalie S Uy,Shumyle Alam,David J. Cohen,Russell J. Crew,Geoffrey K. Dube,Maya K. Rao,Sitharthan Kamalakaran,Brett Copeland,Zhong Ren,Joshua Bridgers,Colin D. Malone,Caroline Mebane,Neha Dagaonkar,Bengt Fellström,Carolina Haefliger,Sumit Mohan,Simone Sanna-Cherchi,Krzysztof Kiryluk,Jan Fleckner,Ruth March,Adam Platt,David Goldstein,Ali G. Gharavi +51 more
TL;DR: Exome sequencing in a combined cohort of more than 3000 patients with chronic kidney disease yielded a genetic diagnosis in just under 10% of cases, with genetic findings for medically actionable disorders that would also lead to subspecialty referral and inform renal management.