E
Eiji Osawa
Researcher at Shinshu University
Publications - 66
Citations - 4574
Eiji Osawa is an academic researcher from Shinshu University. The author has contributed to research in topics: Diamond & Nanodiamond. The author has an hindex of 25, co-authored 62 publications receiving 4158 citations. Previous affiliations of Eiji Osawa include Northwestern University & National Institute of Advanced Industrial Science and Technology.
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Active Nanodiamond Hydrogels for Chemotherapeutic Delivery
TL;DR: Doxorubicin hydrochloride (DOX), an apoptosis-inducing drug widely used in chemotherapy, was successfully applied toward the functionalization of nanodiamond materials (NDs) and introduced toward murine macrophages as well as human colorectal carcinoma cells with preserved efficacy.
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Nanodiamond Therapeutic Delivery Agents Mediate Enhanced Chemoresistant Tumor Treatment
Edward Kai-Hua Chow,Xuan Zhang,Mark Chen,Robert Lam,Erik Robinson,Houjin Huang,Daniel J. Schaffer,Eiji Osawa,Andrei Goga,Dean Ho +9 more
TL;DR: Nanodiamond-based drug delivery significantly enhanced treatment efficacy and safety in multiple chemoresistant cancer models and ND-conjugated chemotherapy represents a promising, biocompatible strategy for overcoming chemoresistance and enhancing chemotherapy efficacy andSafety.
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Polymer-Functionalized Nanodiamond Platforms as Vehicles for Gene Delivery
TL;DR: NDs are introduced as vectors for in vitro gene delivery via surface-immobilization with 800 Da polyethyleneimine (PEI800) and covalent conjugation with amine groups and serve as a rapid, scalable, and broadly applicable gene therapy strategy.
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Enhanced diamond nucleation on monodispersed nanocrystalline diamond
Oliver A. Williams,Olivier Douheret,Olivier Douheret,Michael Daenen,Michael Daenen,Ken Haenen,Ken Haenen,Eiji Osawa,Makoto Takahashi +8 more
TL;DR: In this paper, a method for improving the nucleation density of nanocrystalline diamond growth is demonstrated, where detonation nanodiamond powder was bead-milled and processed to stable aqueous colloid of core particles.
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Nanodiamond-mediated delivery of water-insoluble therapeutics.
TL;DR: A platform approach of water-dispersible, nanodiamond cluster-mediated interactions with several therapeutics to enhance their suspension in water with preserved functionality, thereby enabling novel treatment paradigms that were previously unrealized.