Elahe Keyhani

TL;DR: BPA showed that BPA could lead to chromosomal aberrations in both ER-dependent and independent pathways at some concentrations or in cell types yet not reported, and could probably be considered as a facilitator for some predisposed cells to be cancerous by raising the chromosome instability levels.

TL;DR: Overexpression of the HER-2/neu gene in MMGTs results in similar biological behavior as that of HBC; as a result, these tumors have can be considered to have important similarities in clinicopathological characteristics.

TL;DR: Patients with simultaneous mutations of HER-2 and p53 genes, those with ERBB2 molecular subtype and also younger women seem more eligible for obtaining anti-angiogenic agents in breast cancer via assessment of tumor angiogenesis by the microvessel density (MVD) method and associations with clinicopathological characteristics.

TL;DR: It is suggested that the LCR background, by governing the state of BCL11A binding to this region, plays a more significant role in determining the thalassemia phenotype than the level of B CL11A protein expression, that might be influenced by single nucleotide polymorphisms in intronic regions of the BCL 11A gene.

TL;DR: The sequence variations found within the promoter and 5′-UTR region of the gene warrant expression analysis and screening more tumor samples at this region, and no deleterious mutations were detected in the coding sequence.