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Elangovan Vellaichamy

Researcher at University of Madras

Publications -  53
Citations -  1166

Elangovan Vellaichamy is an academic researcher from University of Madras. The author has contributed to research in topics: Natriuretic peptide & Atrial natriuretic peptide. The author has an hindex of 18, co-authored 47 publications receiving 1013 citations. Previous affiliations of Elangovan Vellaichamy include Cleveland Clinic & Tulane University.

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Quantification of the overall reactive oxygen species scavenging capacity of biological fluids and tissues.

TL;DR: It was hypothesized and then demonstrated that an evaluation of the overall reducing power of a biological sample correlates with the overall scavenging activity of the sample, and in order to quantify the total reducing power, the cyclic voltammetry methodology was applied.
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Influence of cytokines and growth factors in ANG II-mediated collagen upregulation by fibroblasts in rats: role of myocytes.

TL;DR: It is shown that cardiomyocytes induce secretion of active TGF-beta in the presence of ANG II and that a paracrine action of TGF -beta subsequently induces different cytokines (IL-6) in fibroblasts, thereby promoting collagen synthesis.
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Rapid synthesis of biocompatible silver nanoparticles using aqueous extract of Rosa damascena petals and evaluation of their anticancer activity

TL;DR: The results of the present study suggest that G-SNPs can be synthesized rapidly within first minute of the reaction; they are biocompatible and possess anticancer activity against human lung adenocarcinoma.
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Involvement of the NF-κB/Matrix Metalloproteinase Pathway in Cardiac Fibrosis of Mice Lacking Guanylyl Cyclase/Natriuretic Peptide Receptor A

TL;DR: It is demonstrated that disruption of NPRA/cGMP signaling promotes hypertrophic growth and extracellular matrix remodeling, leading to the development of cardiac hypertrophy, myocardial fibrosis, and congestive heart failure.
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Natriuretic peptide receptor A mediates renal sodium excretory responses to blood volume expansion

TL;DR: It is established that NPRA activation is the predominant mechanism mediating the natriuretic, diureic, and renal hemodynamic responses to acute blood volume expansion.