E
Eleanor M. Williams
Researcher at Fred Hutchinson Cancer Research Center
Publications - 8
Citations - 1949
Eleanor M. Williams is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Gene & Gene duplication. The author has an hindex of 8, co-authored 8 publications receiving 1882 citations.
Papers
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Journal ArticleDOI
Human subtelomeres are hot spots of interchromosomal recombination and segmental duplication
Elena V. Linardopoulou,Eleanor M. Williams,Yuxin Fan,Yuxin Fan,Cynthia Friedman,Janet M. Young,Barbara J. Trask,Barbara J. Trask +7 more
TL;DR: Evidence that human subtelomeres arose recently through repeated translocations between chromosome ends is provided and an evolutionary cycle between segmental polymorphisms and genome rearrangements is suggested.
Journal ArticleDOI
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network
Amir Orian,Bas van Steensel,Jeffrey J. Delrow,Harmen J. Bussemaker,Ling Li,Tomoyuki Sawado,Eleanor M. Williams,Lenora W. M. Loo,Shaun M. Cowley,Cynthia Yost,Sarah B. Pierce,Bruce A. Edgar,Susan M. Parkhurst,Robert N. Eisenman +13 more
TL;DR: The DamID method is employed to carry out global genomic mapping of the Drosophila Myc, Max, and Mad/Mnt proteins and suggests that a fundamental aspect of Max network function involves widespread binding and regulation of gene expression.
Dataset
Supplementary Data Only: Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network.
Amir Orian,Bas van Steensel,Jeffrey J. Delrow,Harmen J. Bussemaker,Ling Li,Tomoyuki Sawado,Eleanor M. Williams,Lenora W. M. Loo,Shaun M. Cowley,Cynthia Yost,Sarah B. Pierce,Bruce A. Edgar,Susan M. Parkhurst,Robert N. Eisenman +13 more
TL;DR: In this paper, DamID was employed to carry out global genomic mapping of the Drosophila Myc, Max, and Mad/Mnt proteins, and the results suggest that a fundamental aspect of Max network function involves widespread binding and regulation of gene expression.
Journal ArticleDOI
Different evolutionary processes shaped the mouse and human olfactory receptor gene families
Janet M. Young,Cynthia Friedman,Eleanor M. Williams,Joseph A. Ross,Lori Tonnes-Priddy,Barbara J. Trask +5 more
TL;DR: This study provides the basis for functional studies of the transcriptional regulation and ligand-binding capabilities of the OR gene family, and finds orthologous clusters at syntenic human locations for most mouse genes, indicating that most OR gene clusters predate primate-rodent divergence.
Journal ArticleDOI
Array comparative genomic hybridization analysis of genomic alterations in breast cancer subtypes.
Lenora W. M. Loo,Douglas I. Grove,Eleanor M. Williams,Cassandra L. Neal,Laura Cousens,Elizabeth L. Schubert,Ilona N. Holcomb,Hillary Massa,Jeri Glogovac,Christopher I. Li,Kathleen E. Malone,Janet R. Daling,Jeffrey J. Delrow,Barbara J. Trask,Li Hsu,Peggy L. Porter +15 more
TL;DR: Results indicate that array comparative genomic hybridization can identify significant differences in the genomic alterations between subtypes of breast cancer.