Elena Oliva

TL;DR: Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystemic disorder, belonging to the small vessel anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, defined as an eOSinophil-rich and necrotizing granulOMatous inflammation often involving the respiratory tract, and Necrotizing vasculopathy predominantly affecting small to medium-sized vessels.

TL;DR: Adjuvant immunotherapy with IL-2+IFN-&agr; showed no RFS or OS improvement in RCC patients who underwent radical surgery, and toxicity of immunotherapy was mild and limited to World Health Organization grade 1-2 in most cases.

TL;DR: The PTPN22 620W allele confers susceptibility to the development of GPA (but not of MPA or CSS), and particularly of its ANCA-positive subset.

TL;DR: The main clinical and therapeutic aspects of childhood-onset ANCA-associated vasculitis are reviewed, and preliminary data on demographic characteristics and organ manifestations of an Italian multicentre cohort is provided.

TL;DR: In this prospective, open-label trial, remission was defined as a stable, reduced mass and absence of hydronephrosis, disease-related symptoms and normal inflammatory markers at month 12.