E
Elizabeth H. C. Bromley
Researcher at Durham University
Publications - 38
Citations - 2629
Elizabeth H. C. Bromley is an academic researcher from Durham University. The author has contributed to research in topics: Molecular motor & Synthetic biology. The author has an hindex of 21, co-authored 37 publications receiving 2394 citations. Previous affiliations of Elizabeth H. C. Bromley include University of Cambridge & Western University of Health Sciences.
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Journal ArticleDOI
The binding of thioflavin-T to amyloid fibrils: localisation and implications.
TL;DR: Thioflavin-T binds to amyloid fibrils such that their long axes are parallel, and it is proposed binding occurs in 'channels' that run along the length of the beta-sheet.
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A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology
Jordan M. Fletcher,Aimee L. Boyle,Marc Bruning,Gail J. Bartlett,Thomas L. Vincent,Nathan R. Zaccai,Craig T. Armstrong,Elizabeth H. C. Bromley,Paula J. Booth,R. Leo Brady,Andrew R. Thomson,Derek N. Woolfson +11 more
TL;DR: Pcomp, an on-line registry of peptide components for protein-design and synthetic-biology applications, is introduced, a basis set of de novo designed α-helical coiled-coil peptides that adopt defined and well-characterized parallel dimeric, trimeric, and tetrameric states.
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Peptide and Protein Building Blocks for Synthetic Biology: From Programming Biomolecules to Self-Organized Biomolecular Systems
TL;DR: This work describes how, for certain protein-folding motifs, polypeptide chains can be instructed to fold and combined to give structured complexes, and how protein-based systems may be encapsulated to control and investigate their functions.
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Aggregation across the length-scales in β-lactoglobulin
TL;DR: Polarized light microscopy and Environmental scanning electron microscopy have been used to explore the internal structure of these spherulites under conditions in which the solvent has not been dried off, and it is confirmed that the BLG fibrils show all the classical signatures of amyloid fibril.
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Excited-State Aromatic Interactions in the Aggregation-Induced Emission of Molecular Rotors
Jiri Sturala,Marc K. Etherington,Aisha N. Bismillah,Heather F. Higginbotham,William Trewby,Juan A. Aguilar,Elizabeth H. C. Bromley,Alyssa-Jennifer Avestro,Andrew P. Monkman,Paul R. McGonigal +9 more
TL;DR: The photoluminescence properties of a series of phenyl-ring molecular rotors bearing three, five, six, and seven phenyl groups are reported on, demonstrating that relaxed dimer states can form as a result of intra- or intermolecular interactions across a range of environments in solution and solid samples.