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Elizabeth Rigney
Researcher at John Radcliffe Hospital
Publications - 2
Citations - 192
Elizabeth Rigney is an academic researcher from John Radcliffe Hospital. The author has contributed to research in topics: Antigen & Endoplasmic reticulum. The author has an hindex of 2, co-authored 2 publications receiving 187 citations.
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A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies.
K Micklem,Elizabeth Rigney,Jacqueline Cordell,David Simmons,Paul Stross,Helen Turley,Brian Seed,David Y. Mason +7 more
TL;DR: It was concluded that these six antibodies react with a macrophage‐associated antigen for which the gene has been cloned, and this group of antibodies has recently been designated CD68 by the Fourth Workshop on Human Leucocyte Differentiation Antigens.
Journal ArticleDOI
A Soluble Major Histocompatibility Complex Class I Peptide-binding Platform Undergoes a Conformational Change in Response to Peptide Epitopes
TL;DR: A soluble, truncated form of the mouse H-2Db HC that contains only the peptide binding domains of the class I molecule is expressed, and it is shown that this peptide-binding “platform” is relatively stable in physiological buffers and undergoes a conformational change that is detectable with antibodies, in response to synthetic peptides.