E
Emilia Utomo
Researcher at Queen's University Belfast
Publications - 30
Citations - 593
Emilia Utomo is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 8, co-authored 16 publications receiving 175 citations.
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Journal ArticleDOI
Dissolving microneedle-mediated dermal delivery of itraconazole nanocrystals for improved treatment of cutaneous candidiasis
Andi Dian Permana,Alejandro Javier Paredes,Fabiana Volpe-Zanutto,Qonita Kurnia Anjani,Emilia Utomo,Ryan F. Donnelly +5 more
TL;DR: The concept that the incorporation of ITZ-NCs into dissolving MNs can offer an effective approach for cutaneous candidiasis treatment is verified, and the antifungal activity in anex vivocandidiasis infection model exhibited that the CA viability declined by up to 100% after 48 h of administration.
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Selective delivery of silver nanoparticles for improved treatment of biofilm skin infection using bacteria-responsive microparticles loaded into dissolving microneedles
Andi Dian Permana,Qonita Kurnia Anjani,Sartini,Emilia Utomo,Fabiana Volpe-Zanutto,Alejandro Javier Paredes,Yayu Mulsiani Evary,Sandra Aulia Mardikasari,Muh. Rezky Pratama,Irma Nurfadilah Tuany,Ryan F. Donnelly +10 more
TL;DR: The feasibility of the loading of silver NPs into responsive MPs for improved antibiofilm activities when delivered using DMNs is confirmed and toxicity and in vivo pharmacodynamic studies should now be carried out in an appropriate model.
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Poly(caprolactone)-Based Coatings on 3D-Printed Biodegradable Implants: A Novel Strategy to Prolong Delivery of Hydrophilic Drugs
Sarah A. Stewart,Juan Domínguez-Robles,Victoria J McIlorum,Zoilo Gonzalez,Emilia Utomo,Elena Mancuso,Dimitrios A. Lamprou,Ryan F. Donnelly,Eneko Larrañeta +8 more
TL;DR: This work investigates the use of poly(caprolactone) (PCL)-based implant coatings as a novel strategy to prolong the delivery of hydrophilic compounds from implantable devices that have been prepared by additive manufacturing (AM).
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WITHDRAWN: Bacterially sensitive nanoparticle-based dissolving microneedles of doxycycline for enhanced treatment of bacterial biofilm skin infection: A proof of concept study.
TL;DR: A combination approach of bacterial sensitive nanoparticles (NPs) and dissolving microneedles (MNs) of doxycycline (DOX) for improved biofilm penetration and specifically delivering DOX to the infection site following its formulation into bacterial sensitive NPs and delivery via MN.
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Thermosensitive and mucoadhesive in situ ocular gel for effective local delivery and antifungal activity of itraconazole nanocrystal in the treatment of fungal keratitis
Andi Dian Permana,Rifka Nurul Utami,Patricia Layadi,Achmad Himawan,Nana Juniarti,Qonita Kurnia Anjani,Emilia Utomo,Sandra Aulia Mardikasari,Andi Arjuna,Ryan F. Donnelly +9 more
TL;DR: In this article, the incorporation of itraconazole into nanocrystalline carrier system with stabilizer Pluronic® F127 and was further formulated into thermosensitive in situ ocular gel.