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Emilio Alvarez
Researcher at Hospital General Universitario Gregorio Marañón
Publications - 22
Citations - 1825
Emilio Alvarez is an academic researcher from Hospital General Universitario Gregorio Marañón. The author has contributed to research in topics: Standardized uptake value & Neoadjuvant therapy. The author has an hindex of 14, co-authored 22 publications receiving 1682 citations. Previous affiliations of Emilio Alvarez include Complutense University of Madrid & GlaxoSmithKline.
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Journal ArticleDOI
Thousands of chemical starting points for antimalarial lead identification
Francisco-Javier Gamo,Laura M. Sanz,J. Vidal,Cristina de Cozar,Emilio Alvarez,J.L. Lavandera,Dana E. Vanderwall,Darren V. S. Green,Vinod Kumar,Samiul Hasan,James R. Brown,Catherine E. Peishoff,Lon R. Cardon,Jose F. Garcia-Bustos +13 more
TL;DR: Chemical structures and associated data suggest several novel mechanisms of antimalarial action, such as inhibition of protein kinases and host–pathogen interaction related targets.
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New Compound Sets Identified from High Throughput Phenotypic Screening Against Three Kinetoplastid Parasites: An Open Resource
Imanol Peña,M. Pilar Manzano,Juan Cantizani,Albane Kessler,Julio Alonso-Padilla,Ana I. Bardera,Emilio Alvarez,Gonzalo Colmenarejo,Ignacio Cotillo,Irene Roquero,Francisco de Dios-Anton,Vanessa Barroso,Ana Rodriguez,David W. Gray,Miguel Navarro,Vinod Kumar,Alexander Sherstnev,David H. Drewry,James R. Brown,Jose M. Fiandor,Julio Martin +20 more
TL;DR: Functional analyses of the GlaxoSmithKline high-throughput diversity set of 1.8 million compounds suggest a wide array of potential modes of action against kinetoplastid kinases, proteases and cytochromes as well as potential host–pathogen targets.
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18F-FDG positron emission tomography staging and restaging in rectal cancer treated with preoperative chemoradiation
Felipe A. Calvo,Marta Domper,Raúl Matute,Raul Martinez-Lazaro,J.A. Arranz,Manuel Desco,Emilio Alvarez,José Luis Carreras +7 more
TL;DR: Preliminary results observed suggest the potential utility of FDG-PET as a complementary diagnostic procedure in the initial clinical evaluation as well as in the assessment of chemoradiation response (any T downstaged event) of locally advanced rectal cancer.
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Screening and catalytic activity in organic synthesis of novel fungal and yeast lipases
Fernando Cardenas,Emilio Alvarez,Maria-Soledad de Castro-Alvarez,J.M. Sánchez-Montero,Manuel Valmaseda,Steve W. Elson,Jose‐Vicente Sinisterra +6 more
TL;DR: Achremonium murorum, Monascus mucoroides, Arthroderma ciferri, Fusarium poae, Ovadendron sulphureo-ochraceum and Rhodotorula araucariae are described as lipase-producers for the first time and were tested as biocatalysts in several organic reactions using unnatural substrates.
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Prognostic factors for disease-free survival in patients with T3-4 or N+ rectal cancer treated with preoperative chemoradiation therapy, surgery, and intraoperative irradiation.
J.A. Diaz-Gonzalez,Felipe A. Calvo,Javier Cortes,J.L. Garcia-Sabrido,M. Gomez-Espi,Emilio del Valle,Fernando Muñoz-Jiménez,Emilio Alvarez +7 more
TL;DR: Females with an intense pathologic response to preoperative chemoradiotherapy have an excellent 3-year disease-free survival and this information might be of interest for stratification of patients in the development of adjuvant treatment trials.