J
Jose F. Garcia-Bustos
Researcher at University of Melbourne
Publications - 63
Citations - 4829
Jose F. Garcia-Bustos is an academic researcher from University of Melbourne. The author has contributed to research in topics: Haemonchus contortus & Peptidoglycan. The author has an hindex of 28, co-authored 63 publications receiving 4370 citations. Previous affiliations of Jose F. Garcia-Bustos include University of Basel & Hospital General Universitario Gregorio Marañón.
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Journal ArticleDOI
Thousands of chemical starting points for antimalarial lead identification
Francisco-Javier Gamo,Laura M. Sanz,J. Vidal,Cristina de Cozar,Emilio Alvarez,J.L. Lavandera,Dana E. Vanderwall,Darren V. S. Green,Vinod Kumar,Samiul Hasan,James R. Brown,Catherine E. Peishoff,Lon R. Cardon,Jose F. Garcia-Bustos +13 more
TL;DR: Chemical structures and associated data suggest several novel mechanisms of antimalarial action, such as inhibition of protein kinases and host–pathogen interaction related targets.
Journal ArticleDOI
Nuclear protein localization.
TL;DR: Dans une derniere partie, le mecanisme de the translocation et sa regulation sont discutes.
Journal ArticleDOI
Two-dimensional single-cell patterning with one cell per well driven by surface acoustic waves
David J. Collins,Belinda Joan Morahan,Jose F. Garcia-Bustos,Christian Doerig,Magdalena Plebanski,Adrian Neild +5 more
TL;DR: A new method for the patterning of multiple spatially separated single particles and cells using high-frequency acoustic fields with one cell per acoustic well is introduced, made possible by a hitherto unexplored regime where the acoustic wavelength is on the same order as the cell dimensions.
Journal ArticleDOI
Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis.
Lluis Ballell,Robert H. Bates,Robert J. Young,Daniel Alvarez-Gomez,Emilio Alvarez-Ruiz,Vanessa Barroso,Delia Blanco,Benigno Crespo,Jaime Escribano,Ruben R. Gonzalez,Sonia Lozano,Sophie Huss,Angel Santos-Villarejo,Jose Julio Martin-Plaza,Alfonso Mendoza,María José Rebollo-López,Modesto Jesus Remuinan-Blanco,Jose Luis Lavandera,Esther Pérez-Herrán,Francisco Javier Gamo-Benito,Jose F. Garcia-Bustos,David Barros,Julia Castro,Nicholas Cammack +23 more
TL;DR: With the aim of fuelling open‐source, translational, early‐stage drug discovery activities, the results of the recently completed antimycobacterial phenotypic screening campaign against Mycobacterium bovis BCG with hit confirmation in M. tuberculosis H37Rv were made publicly accessible.
Journal ArticleDOI
Nitric oxide-producing CD11b+Ly-6G(Gr-1)+CD31(ER-MP12)+cells in the spleen of cyclophosphamide–treated mice: implications for T-cell responses in immunosuppressed mice
Iñigo Angulo,Iñigo Angulo,Federico Gómez de las Heras,Federico Gómez de las Heras,Jose F. Garcia-Bustos,Jose F. Garcia-Bustos,Domingo Gargallo,Domingo Gargallo,M. Ángeles Muñoz-Fernández,M. Ángeles Muñoz-Fernández,Manuel Fresno,Manuel Fresno +11 more
TL;DR: The results indicated that CTX might also cause immunosuppression by a mechanism involving the presence of immature myeloid cells with suppressor activity, which may have implications in clinical praxis since inappropriate immunotherapies in patients treated with intensive chemotherapy could lead to deleterious T-cell responses.