E
Emily K. Jackson
Researcher at Howard Hughes Medical Institute
Publications - 2
Citations - 899
Emily K. Jackson is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Chemistry & Primer (cosmetics). The author has an hindex of 1, co-authored 1 publications receiving 703 citations.
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Journal ArticleDOI
Chromothripsis from DNA damage in micronuclei
Cheng-Zhong Zhang,Alexander Spektor,Hauke Cornils,Joshua M. Francis,Emily K. Jackson,Shiwei Liu,Matthew Meyerson,David Pellman +7 more
TL;DR: It is demonstrated that micronucleus formation can indeed generate a spectrum of genomic rearrangements, some of which recapitulate all known features of chromothripsis.
Posted ContentDOI
Seq-ing the SINEs of Central Nervous System Tumors in Cerebrospinal Fluid DNA
Christopher Douville,Sarah Curtis,Matthew G. Summers,Tej D. Azad,Jordina Rincon-Torroella,Bracha Erlanger Avigdor,Jonathan C. Dudley,Joshua Materi,Dheeraj Raj,S. Asha Nair,Debarati Bhanja,Kieran Tuohy,Lisa Dobbyn,Maria Popoli,Janine Ptak,N. Nehme,Natalie Silliman,Cherie Blair,Kim Judge,Gary L. Gallia,M Groves,C. Jackson,Emily K. Jackson,John Laterra,Malcolm Lim,Deborah Mukherjee,Jon D. Weingart,J. Naidoo,Carl Koschmann,Nathan D. Smith,Karisa C. Schreck,C. Paro-Villamizar,M. Glatnz,Matthias Holdhoff,K. W. Kinzler,Nickolas Papadopoulos,Bert Vogelstein,Chetan Bettegowda +37 more
TL;DR: Real-CSF as discussed by the authors uses machine learning to assess three features from the sequencing data - gains or losses of 39 chromosome arms, focal amplifications, and somatic nucleotide variants.