Emily MacLean

TL;DR: Higher quality clinical studies assessing the diagnostic accuracy of serological tests for covid-19 are urgently needed, as available evidence does not support the continued use of existing point-of-care serological Tests for coronavirus disease-2019.

TL;DR: TB biomarker discovery studies are often poorly designed and findings are rarely confirmed in independent studies, so few markers progress to a further developmental stage, according to a systematic review.

TL;DR: A wide array of molecular tests for TB detection is being developed and evaluated, and while some tests are intended for reference laboratory use, others are being aimed at the point-of-care and peripheral health care settings.

TL;DR: Stool Xpert could be a noninvasive method of ruling in PTB in children, particularly those with HIV, and generalizability of the evidence is limited by the lack of standardized stool preparation and testing protocols.

TL;DR: A well-curated and user-friendly TB biomarker database that will simplify data and knowledge sharing, empower collaboration, help in the coordination of efforts and allocation of resources, streamline the verification and validation of biomarker candidates, and ultimately lead to an accelerated translation into clinically useful tools.