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Emma L. Culver
Researcher at University of Oxford
Publications - 84
Citations - 2178
Emma L. Culver is an academic researcher from University of Oxford. The author has contributed to research in topics: Primary sclerosing cholangitis & Medicine. The author has an hindex of 20, co-authored 64 publications receiving 1684 citations. Previous affiliations of Emma L. Culver include John Radcliffe Hospital & National Institute for Health Research.
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Journal ArticleDOI
Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis
Phil A. Hart,Terumi Kamisawa,William R. Brugge,Jae Bock Chung,Emma L. Culver,László Czakó,Luca Frulloni,Vay Liang W. Go,Thomas M. Gress,Myung-Hwan Kim,Shigeyuki Kawa,Kyu Taek Lee,Markus M. Lerch,Wei-Chih Liao,Matthias Löhr,Kazuichi Okazaki,Ji Kon Ryu,Nicolas Schleinitz,Kyoko Shimizu,Tooru Shimosegawa,Roy Soetikno,George Webster,Dhiraj Yadav,Yoh Zen,Suresh T. Chari +24 more
TL;DR: In this article, the authors set out to better understand the current burden of AIP at several academic institutions diagnosed using the International Consensus Diagnostic Criteria, and to describe long-term outcomes, including organs involved, treatments, relapse frequency and longterm sequelae.
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Type 1 Autoimmune Pancreatitis and IgG4-Related Sclerosing Cholangitis Is Associated With Extrapancreatic Organ Failure, Malignancy, and Mortality in a Prospective UK Cohort
Matthew T. Huggett,Matthew T. Huggett,Emma L. Culver,Emma L. Culver,Mithilesh Kumar,J.M. Hurst,Manuel Rodriguez-Justo,Michael H. Chapman,Gavin Johnson,Stephen P. Pereira,Stephen P. Pereira,Roger W. Chapman,Roger W. Chapman,George Webster,Eleanor Barnes,Eleanor Barnes +15 more
TL;DR: The findings suggest that AIP and IgG4-SC are associated with significant morbidity and mortality owing to extrapancreatic organ failure and malignancy.
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Serum Immunoglobulin G4 and Immunoglobulin G1 for Distinguishing Immunoglobulin G4-Associated Cholangitis From Primary Sclerosing Cholangitis
Kirsten Boonstra,Emma L. Culver,Lucas Maillette de Buy Wenniger,Marianne J. Van Heerde,Karel J. van Erpecum,Alexander C. Poen,Karin M.J. van Nieuwkerk,B W Marcel Spanier,Ben J.M. Witteman,H.A.R.E. Tuynman,Nan van Geloven,Henk R. van Buuren,Roger W. Chapman,Eleanor Barnes,Ulrich Beuers,Cyriel Y. Ponsioen +15 more
TL;DR: A new diagnostic algorithm based on IgG4/IgG1 ratio that may be used in clinical practice to distinguish IAC from PSC is proposed and significantly improved PPV and specificity.
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Elevated Serum IgG4 Levels in Diagnosis, Treatment Response, Organ Involvement, and Relapse in a Prospective IgG4-Related Disease UK Cohort.
Emma L. Culver,Ross Sadler,Dawn Simpson,Tamsin Cargill,Tamsin Cargill,M Makuch,Adrian C Bateman,Anthony Ellis,Jane Collier,Roger W. Chapman,Roger W. Chapman,Paul Klenerman,Paul Klenerman,Eleanor Barnes,Eleanor Barnes,Berne Ferry +15 more
TL;DR: Serum IgG4 levels are elevated in multiple non-IgG4-RD inflammatory and malignant conditions, with less than one-quarter of those with an elevated IgG 4 meeting IgG3-RD diagnostic criteria, and a serum IgG5 of ≥2.8 g l−1 at diagnosis was associated with multi-organ involvement and risk of relapse.
Journal ArticleDOI
Increases in IgE, Eosinophils, and Mast Cells Can be Used in Diagnosis and to Predict Relapse of IgG4-Related Disease
Emma L. Culver,Ross Sadler,Adrian C Bateman,M Makuch,Tamsin Cargill,Tamsin Cargill,Berne Ferry,Rob C. Aalberse,Eleanor Barnes,Eleanor Barnes,Theo Rispens +10 more
TL;DR: In a prospective study, IgG4‐RD is associated with allergy, atopy, eosinophilia, increased serum levels of IgE, and IgE‐positive mast cells in lymphoid, biliary, and pancreatic tissue.