Emma L. Prescott

TL;DR: A new function of MCPyV small T antigen (ST) is identified as an inhibitor of NF-κB-mediated transcription, allowing establishment of early or persistent infection within the host cell.

TL;DR: The architecture of the major structural protein components of these human polyomaviruses are similar to previous structures from other hosts, but give new insight into the location and role of the enigmatic minor structural proteins, VP2 and VP3.

TL;DR: This review article summarizes the latest understanding of this enigmatic oncoprotein, including its role in the HPV life cycle, interactions with host proteins and contribution toward tumorigenesis.

TL;DR: It is demonstrated that the agnoprotein binding partner α-soluble N-ethylmaleimide sensitive fusion (NSF) attachment protein (α-SNAP) is necessary for BK virion release, and siRNA knockdown of α- SNAP prevents nuclear release of wild-type BKvirions.

TL;DR: In this paper , the authors demonstrate that agnoprotein shows properties associated with viroporins, a group of virus-encoded membrane spanning proteins that play key roles in virus infection and release.