E
Emmanuel Pham
Publications - 2
Citations - 328
Emmanuel Pham is an academic researcher. The author has contributed to research in topics: Cancer & Engineering. The author has an hindex of 1, co-authored 1 publications receiving 300 citations.
Papers
More filters
Journal ArticleDOI
Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer.
Sylvia Julien,Ana Merino-Trigo,Ludovic Lacroix,Marc Pocard,Diane Goéré,Pascale Mariani,Sophie Landron,Ludovic Bigot,Fariba Nemati,Peggy Dartigues,Louis-Bastien Weiswald,Denis Lantuas,Loïc Morgand,Emmanuel Pham,Patrick Gonin,Virginie Dangles-Marie,Bastien Job,Philippe Dessen,Alain Bruno,Alain Pierré,Hany Soliman,Manoel Nunes,Guillaume Lardier,Loreley Calvet,Brigitte Demers,Gregoire Prevost,Patricia Vrignaud,Sergio Roman-Roman,Olivier Duchamp,Cyril Berthet +29 more
TL;DR: An extensive in vivo analysis of patient-derived xenograft models for CRC shows the loss of human stroma cells after engraftment, observed a metastatic phenotype in some models, and compared the molecular profile with the drug sensitivity of each tumor model.
Journal ArticleDOI
Solving the Evidence Interpretability Crisis in Health Technology Assessment: A Role for Mechanistic Models?
Eulalie Courcelles,Jean-Pierre Boissel,Jacques Massol,Ingrid Klingmann,Riad Kahoul,Marc Hommel,Emmanuel Pham,Alexander Kulesza +7 more
TL;DR: Light is shed on different stakeholder's contributions and needs in the appraisal phase and how mechanistic modeling strategies and reporting can contribute to this effort to implement mechanistic models central in the evidence generation, synthesis, and appraisal of HTA so that the totality of mechanistic and clinical evidence can be leveraged by all relevant stakeholders.