s, or keywords if they used Heck-type chemistry in their syntheses, because it became one of basic tools of organic preparations, a natural way to

http://aether.cmi.ua.ac.be/artikels/Artikels%20Gitte/Artikels/Reviews/Heck%20reactie%20Beletskaya%20%20Chem.%20Rev.%20003009.pdf

The heck reaction as a sharpening stone of palladium catalysis.

Catalytic dehydrogenative cross-coupling: forming carbon-carbon bonds by oxidizing two carbon-hydrogen bonds

/pdf/aryl-aryl-bond-formation-one-century-after-the-discovery-of-1jdyxlkwix.pdf

Aryl-aryl bond formation one century after the discovery of the Ullmann reaction.

The biaryl structural motif is a predominant feature in many pharmaceutically relevant and biologically active compounds. As a result, for over a century 1 organic chemists have sought to develop new and more efficient aryl -aryl bond-forming methods. Although there exist a variety of routes for the construction of aryl -aryl bonds, arguably the most common method is through the use of transition-metalmediated reactions. 2-4 While earlier reports focused on the use of stoichiometric quantities of a transition metal to carry out the desired transformation, modern methods of transitionmetal-catalyzed aryl -aryl coupling have focused on the development of high-yielding reactions achieved with excellent selectivity and high functional group tolerance under mild reaction conditions. Typically, these reactions involve either the coupling of an aryl halide or pseudohalide with an organometallic reagent (Scheme 1), or the homocoupling of two aryl halides or two organometallic reagents. Although a number of improvements have developed the former process into an industrially very useful and attractive method for the construction of aryl -aryl bonds, the need still exists for more efficient routes whereby the same outcome is accomplished, but with reduced waste and in fewer steps. In particular, the obligation to use coupling partners that are both activated is wasteful since it necessitates the installation and then subsequent disposal of stoichiometric activating agents. Furthermore, preparation of preactivated aryl substrates often requires several steps, which in itself can be a time-consuming and economically inefficient process.

http://aether.cmi.ua.ac.be/artikels/Artikels%20Gitte/Artikels/Reviews/Heck-Type-lautens.pdf

Aryl-aryl bond formation by transition-metal-catalyzed direct arylation.

N-Heterocyclic Carbenes in Late Transition Metal Catalysis

A catalyst has been tuned to make different compounds from the same molecules in carbon–nitrogen bond-forming reactions, depending on the conditions used. The products are potential building blocks for biologically active molecules.

Organic chemistry: One catalyst, two reactions

Plusieurs alkyldibenzothiophenes substitues par des groupements alkyles en position 4 et 6 ont ete synthetises. Nous avons compare leur reactivite en hydrodesulfuration sur un catalyseur industriel NiMo/Al 2 O 3 dans un reacteur ferme a 573 K et sous une pression d'hydrogene de 5 MPa. Il a ete demontre que leur reactivite etait directement liee a l'encombrement autour de l'atome de soufre, l'etape limitante de leur transformation etant la rupture de la liaison C-S. Nous decrivons ensuite une nouvelle methode d'elimination de ces composes refractaires a l'hydrotraitement. Cette methode est basee sur l'analyse de proprietes physico-chimiques des composes refractaires et utilise la formation selective de complexes de transfert de charge (CTC) entre le 4.6-dimethyldibenzothiophene et la tetranitrofluorenone en solution synthetique. La procedure a ete etendue aux coupes gazoles et conduit a une baisse significative de leur taux de soufre.

How could organic synthesis help the understanding of the problems of deep hydrodesulfurization of gasoils

Heterogeneous Enantioselective Catalytic Reduction of Ketones.

La synthese de deux monomeres du thiophene substitues en position 3 par des chaines alkyles chirales a ete realisee. Les potentialites enantioselectives des polymeres chiraux obtenus par polymerisation electrochimique sont etudiees par voltamperometrie cyclique: il semblerait que l'electrolyte et le solvant utilises pendant la polymerisahon conditionnent la conformation et l'electroactivite du polymere chiral

Emmanuelle Schulz

Papers

Organic chemistry: One catalyst, two reactions

How could organic synthesis help the understanding of the problems of deep hydrodesulfurization of gasoils

Heterogeneous Enantioselective Catalytic Reduction of Ketones.

Synthèse et polymérisation de thiophènes substitués en 3 par des chaînes alkyles chirales

Poly-NAP as Ligand for the Asymmetric Hydrogenation of Ketones.