s, or keywords if they used Heck-type chemistry in their syntheses, because it became one of basic tools of organic preparations, a natural way to

http://aether.cmi.ua.ac.be/artikels/Artikels%20Gitte/Artikels/Reviews/Heck%20reactie%20Beletskaya%20%20Chem.%20Rev.%20003009.pdf

The heck reaction as a sharpening stone of palladium catalysis.

Catalytic dehydrogenative cross-coupling: forming carbon-carbon bonds by oxidizing two carbon-hydrogen bonds

/pdf/aryl-aryl-bond-formation-one-century-after-the-discovery-of-1jdyxlkwix.pdf

Aryl-aryl bond formation one century after the discovery of the Ullmann reaction.

The biaryl structural motif is a predominant feature in many pharmaceutically relevant and biologically active compounds. As a result, for over a century 1 organic chemists have sought to develop new and more efficient aryl -aryl bond-forming methods. Although there exist a variety of routes for the construction of aryl -aryl bonds, arguably the most common method is through the use of transition-metalmediated reactions. 2-4 While earlier reports focused on the use of stoichiometric quantities of a transition metal to carry out the desired transformation, modern methods of transitionmetal-catalyzed aryl -aryl coupling have focused on the development of high-yielding reactions achieved with excellent selectivity and high functional group tolerance under mild reaction conditions. Typically, these reactions involve either the coupling of an aryl halide or pseudohalide with an organometallic reagent (Scheme 1), or the homocoupling of two aryl halides or two organometallic reagents. Although a number of improvements have developed the former process into an industrially very useful and attractive method for the construction of aryl -aryl bonds, the need still exists for more efficient routes whereby the same outcome is accomplished, but with reduced waste and in fewer steps. In particular, the obligation to use coupling partners that are both activated is wasteful since it necessitates the installation and then subsequent disposal of stoichiometric activating agents. Furthermore, preparation of preactivated aryl substrates often requires several steps, which in itself can be a time-consuming and economically inefficient process.

http://aether.cmi.ua.ac.be/artikels/Artikels%20Gitte/Artikels/Reviews/Heck-Type-lautens.pdf

Aryl-aryl bond formation by transition-metal-catalyzed direct arylation.

N-Heterocyclic Carbenes in Late Transition Metal Catalysis

Asymmetric hydroamination allows the direct and selective formation of a new CN bond as a simple procedure towards valuable scalemic synthons. Huge efforts have recently been made to overcome the challenges associated with this transformation. This non-comprehensive Concept article aims at pointing out the most recent and original progresses, offering nearby developments, and addressing the next challenges.

Asymmetric Hydroamination: A Survey of the Most Recent Developments

Sulfoxide-Controlled Stereoselective Aza-Piancatelli Reaction

The invention concerns a complexing agent comprising a π electron acceptor, characterised in that the π electron acceptor is an organic compound and has a LUMO energy level not more that - 1 eV, and said electron acceptor is grafted via a binding compound on an organic surface of the support.

Complexing agent based on a $g(p) electron acceptor, preparation and uses thereof

A modified version of the IMPACT heteronuclear multiple bond correlation (HMBC) has allowed the characterization of an organosilane and a tetrasilylated yttrium complex. With the help of this sequence, an average gain in sensitivity close to 2 has been obtained compared with the standard HMBC experiment for disilanes as well as for yttrium complexes containing silylated ligands. This modified version of this long-range correlation experiment opens the way for following kinetics in the range of a fraction of a minute and to study by NMR low concentrated samples and low abundant nuclei. Copyright © 2013 John Wiley & Sons, Ltd.

29Si-1H IMPACT HMBC: a suitable tool for analyzing silylated derivatives.

The use of sulfur-coordinating chiral ligands in the palladium-catalyzed asymmetric Tsuji—Trost reaction is reviewed.

Emmanuelle Schulz

Papers

Asymmetric Hydroamination: A Survey of the Most Recent Developments

Sulfoxide-Controlled Stereoselective Aza-Piancatelli Reaction

Complexing agent based on a $g(p) electron acceptor, preparation and uses thereof

29Si-1H IMPACT HMBC: a suitable tool for analyzing silylated derivatives.

New sulfur-coordinating chiral ligands for the Tsuji—Trost reaction