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Enrico V. Avvedimento
Researcher at University of Naples Federico II
Publications - 100
Citations - 7536
Enrico V. Avvedimento is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Protein kinase A & DNA damage. The author has an hindex of 47, co-authored 98 publications receiving 7065 citations. Previous affiliations of Enrico V. Avvedimento include Mario Negri Institute for Pharmacological Research & Columbia University.
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Journal ArticleDOI
Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis.
Silvia Baroni,Mariarosaria Santillo,Federica Bevilacqua,Michele Maria Luchetti,Tatiana Spadoni,Matteo Mancini,Paolo Fraticelli,Paola Sambo,Ada Funaro,Andrius Kazlauskas,Enrico V. Avvedimento,Armando Gabrielli +11 more
TL;DR: Stimulatory autoantibodies against PDGFR appear to be a specific hallmark of scleroderma and their biologic activity on fibroblasts strongly suggests that they have a causal role in the pathogenesis of the disease.
Journal ArticleDOI
DNA Oxidation as Triggered by H3K9me2 Demethylation Drives Estrogen-Induced Gene Expression
Bruno Perillo,Maria Neve Ombra,Alessandra Bertoni,Concetta Cuozzo,Silvana Sacchetti,Annarita Sasso,Lorenzo Chiariotti,Antonio Malorni,Ciro Abbondanza,Enrico V. Avvedimento +9 more
TL;DR: This work analyzed how H3 histone methylation and demethylation control expression of estrogen-responsive genes and shows that a DNA-bound estrogen receptor directs transcription by participating in bending chromatin to contact the RNA polymerase II recruited to the promoter.
Journal ArticleDOI
The biological functions of A-kinase anchor proteins
TL;DR: The AKAP transduceosome thus optimizes the amplitude and the signal/noise ratio of cAMP-PKA stimuli travelling from the membrane to the nucleus and other subcellular compartments.
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Expression of thyrotropin-receptor mRNA in healthy and Graves' disease retro-orbital tissue
Antonio Feliciello,Antonio Porcellini,Ilaria Ciullo,G Bonavolontà,Enrico V. Avvedimento,Gianfranco Fenzi +5 more
TL;DR: It is shown, by polymerase chain reaction amplification of specific cDNA, that mature TSH-R mRNA is expressed in the retro-orbital tissue of both healthy subjects and patients with Graves' disease.
Journal ArticleDOI
Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo
Ciro Indolfi,Enrico V. Avvedimento,Antonio Rapacciuolo,Emilio Di Lorenzo,Giovanni Esposito,Eugenio Stabile,Antonio Feliciello,Evelina Mele,Paola Giuliano,Gianluigi Condorelli,Massimo Chiariello +10 more
TL;DR: A key role for ras is indicated in smooth muscle cell proliferation and the local delivery of transdominant negative mutants of ras in vivo might prevent some of the acute vascular injury caused by balloon injury.