E
Ergin Beyret
Researcher at Yale University
Publications - 5
Citations - 1203
Ergin Beyret is an academic researcher from Yale University. The author has contributed to research in topics: Piwi-interacting RNA & Argonaute. The author has an hindex of 4, co-authored 5 publications receiving 1104 citations. Previous affiliations of Ergin Beyret include Duke University.
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Journal ArticleDOI
A novel class of small RNAs in mouse spermatogenic cells
TL;DR: A novel class of small RNAs in the mouse male germline termed piwi-interacting RNAs (piRNAs) are identified, associated with MIWI, a spermatogenesis-specific PIWI subfamily member of the Argonaute protein family, suggesting their potential role in translational regulation.
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MILI, a PIWI-interacting RNA-binding Protein, Is Required for Germ Line Stem Cell Self-renewal and Appears to Positively Regulate Translation
Yingdee Unhavaithaya,Yi Hao,Ergin Beyret,Ergin Beyret,Hang Yin,Hang Yin,Satomi Kuramochi-Miyagawa,Toru Nakano,Haifan Lin,Haifan Lin +9 more
TL;DR: It is shown that MILI, a murine PIWI protein, is expressed in the cytoplasm of testicular germ line stem cells, spermatogonia, and early sperMatocytes, where it is enriched in chromatoid bodies, indicating that MILi may positively regulate translation and that such regulation is required for germ linestem cell self-renewal.
Journal ArticleDOI
piRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism
Ergin Beyret,Na Liu,Haifan Lin +2 more
TL;DR: This work identified and characterized large populations of piRNAs in the adult and postnatal developing testes associated with MILI and MIWI, the only PIWI proteins detectable in these testes, and indicates that the adult testicularpiRNAs are predominantly, if not exclusively, produced by a primary processing mechanism instead of the ping-pong mechanism.
Journal ArticleDOI
Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse.
Ergin Beyret,Haifan Lin +1 more
TL;DR: The cytological characterization of piRNAs in the adult mouse testis and the phenotypic analysis of Miwi(-/-); Mili(-/-) mice show thatpiRNAs are specifically present in germ cells, especially abundant in spermatocytes and early round sperMatids, regardless of the type of the genomic sequences to which they correspond.