E
Eri S. Srivatsan
Researcher at University of California, Los Angeles
Publications - 59
Citations - 3303
Eri S. Srivatsan is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Tumor suppressor gene. The author has an hindex of 24, co-authored 56 publications receiving 2891 citations. Previous affiliations of Eri S. Srivatsan include Veterans Health Administration & United States Department of Veterans Affairs.
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Journal ArticleDOI
Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
Reason Wilken,Mysore S. Veena,Mysore S. Veena,Marilene B. Wang,Marilene B. Wang,Eri S. Srivatsan,Eri S. Srivatsan +6 more
TL;DR: An overview of the current in vitro and in vivo data supporting its therapeutic activity in head and neck cancer as well as some of the challenges concerning its development as an adjuvant chemotherapeutic agent are presented.
Journal ArticleDOI
Cellular senescence and tumor suppressor gene p16.
TL;DR: The p16‐mediated senescence acts through the retinoblastoma (Rb) pathway inhibiting the action of the cyclin dependant kinases leading to G1 cell cycle arrest, and Regulation of p16 expression is complex and involves epigenetic control and multiple transcription factors.
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Liposome-Encapsulated Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma In vitro and in Xenografts through the Inhibition of Nuclear Factor κB by an AKT-Independent Pathway
Dorothy Wang,Mysore S. Veena,Kerry Stevenson,Christopher S. Tang,Baran Ho,Jeffrey D. Suh,Victor M. Duarte,Kym F. Faull,Kapil Mehta,Eri S. Srivatsan,Marilene B. Wang +10 more
TL;DR: It is suggested that liposomal curcumin is a viable nontoxic therapeutic agent for HNSCC that may work via an AKT-independent pathway and result in a dose-dependent growth suppression of both cell lines.
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Curcumin suppresses growth of head and neck squamous cell carcinoma
Maria M. LoTempio,Mysore S. Veena,Helen L. Steele,Bharathi Ramamurthy,Tirunelveli S. Ramalingam,Alen N. Cohen,Rita Chakrabarti,Eri S. Srivatsan,Marilene B. Wang +8 more
TL;DR: In this article, curcumin was applied as a noninvasive topical paste to the tumors and inhibition of tumor growth was observed in xenografts from the CAL27 cell line.
Journal ArticleDOI
Cyclin D1 amplification and p16(MTS1/CDK4I) deletion correlate with poor prognosis in head and neck tumors.
Ali Namazie,Sassan Alavi,Olufunmilayo I. Olopade,Giovanni Pauletti,Neema Aghamohammadi,Mazda Aghamohammadi,Jeffrey Gornbein,Thomas C. Calcaterra,Dennis J. Slamon,Marilene B. Wang,Marilene B. Wang,Eri S. Srivatsan +11 more
TL;DR: In this paper, the authors used fluorescence in situ hybridization (FISH) to study cyclin D1 amplification and p16 gene deletion in head and neck tumors and showed that these two genetic aberrations together portend a poorer outcome than either of the abnormalities alone.