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Eric Fain

Researcher at St. Jude Medical

Publications -  14
Citations -  4719

Eric Fain is an academic researcher from St. Jude Medical. The author has contributed to research in topics: Atrial fibrillation & Stroke. The author has an hindex of 11, co-authored 13 publications receiving 4273 citations. Previous affiliations of Eric Fain include Goethe University Frankfurt.

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Prophylactic Use of an Implantable Cardioverter-Defibrillator After Acute Myocardial Infarction

TL;DR: Prophylactic ICD therapy does not reduce overall mortality in high-risk patients who have recently had a myocardial infarction, and is associated with a reduction in the rate of death due to arrhythmia, that was offset by an increase in the rates of death from nonarrhythmic causes.
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Comparison of β-Blockers, Amiodarone Plus β-Blockers, or Sotalol for Prevention of Shocks From Implantable Cardioverter Defibrillators: The OPTIC Study: A Randomized Trial

TL;DR: Despite use of advanced ICD technology and treatment with a beta-blocker, shocks occur commonly in the first year after ICD implant, and amiodarone plus beta- blocker is effective for preventing these shocks and is more effective than sotalol but has an increased risk of drug-related adverse effects.
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Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial

TL;DR: Although amiodarone increased DFT, the effect size with modern ICD systems is very small, and DFT reassessment after the institution of antiarrhythmic drug therapy with amioarone or sotalol is not routinely required.