E
Eric Fain
Researcher at St. Jude Medical
Publications - 14
Citations - 4719
Eric Fain is an academic researcher from St. Jude Medical. The author has contributed to research in topics: Atrial fibrillation & Stroke. The author has an hindex of 11, co-authored 13 publications receiving 4273 citations. Previous affiliations of Eric Fain include Goethe University Frankfurt.
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Journal ArticleDOI
Subclinical Atrial Fibrillation and the Risk of Stroke
Jeff S. Healey,Stuart J. Connolly,Michael R. Gold,Carsten W. Israel,Isabelle C. Van Gelder,Alessandro Capucci,Chu-Pak Lau,Eric Fain,Sean Yang,Christophe Bailleul,Carlos A. Morillo,Mark A. Carlson,Ellison Themeles,Elizabeth S. Kaufman,Stefan H. Hohnloser +14 more
TL;DR: Subclinical atrial tachyarrhythmias, without clinical atrial fibrillation, occurred frequently in patients with pacemakers and were associated with a significantly increased risk of ischemic stroke or systemic embolism.
Journal ArticleDOI
Prophylactic Use of an Implantable Cardioverter-Defibrillator After Acute Myocardial Infarction
Stefan H. Hohnloser,Karl-Heinz Kuck,Paul Dorian,Robin S. Roberts,John R. Hampton,Robert Hatala,Eric Fain,Michael Gent,Stuart J. Connolly +8 more
TL;DR: Prophylactic ICD therapy does not reduce overall mortality in high-risk patients who have recently had a myocardial infarction, and is associated with a reduction in the rate of death due to arrhythmia, that was offset by an increase in the rates of death from nonarrhythmic causes.
Journal ArticleDOI
Comparison of β-Blockers, Amiodarone Plus β-Blockers, or Sotalol for Prevention of Shocks From Implantable Cardioverter Defibrillators: The OPTIC Study: A Randomized Trial
Stuart J. Connolly,Paul Dorian,Robin S. Roberts,Michael Gent,Steven Bailin,Eric Fain,Kevin E. Thorpe,Jean Champagne,Mario Talajic,Benoit Coutu,Gerian Grönefeld,Stefan H. Hohnloser +11 more
TL;DR: Despite use of advanced ICD technology and treatment with a beta-blocker, shocks occur commonly in the first year after ICD implant, and amiodarone plus beta- blocker is effective for preventing these shocks and is more effective than sotalol but has an increased risk of drug-related adverse effects.
Journal ArticleDOI
Temporal Relationship Between Subclinical Atrial Fibrillation and Embolic Events
Michela Brambatti,Stuart J. Connolly,Michael R. Gold,Carlos A. Morillo,Alessandro Capucci,Carmine Muto,C.-P. Lau,Isabelle C. Van Gelder,Stefan H. Hohnloser,Mark A. Carlson,Eric Fain,Juliet Nakamya,Georges H. Mairesse,Marta Halytska,Wei Q. Deng,Carsten W. Israel,Jeff S. Healey +16 more
TL;DR: Although SCAF is associated with an increased risk of stroke and embolism, very few patients had SCAF in the month before their event, and only 1 of these 4 patients was experiencing SCAF at the time of the stroke.
Journal ArticleDOI
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial
Stefan H. Hohnloser,Paul Dorian,Robin S. Roberts,Michael Gent,Carsten W. Israel,Eric Fain,Jean Champagne,Stuart J. Connolly +7 more
TL;DR: Although amiodarone increased DFT, the effect size with modern ICD systems is very small, and DFT reassessment after the institution of antiarrhythmic drug therapy with amioarone or sotalol is not routinely required.