J
John R. Hampton
Researcher at Goethe University Frankfurt
Publications - 10
Citations - 5831
John R. Hampton is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Myocardial infarction & Streptokinase. The author has an hindex of 9, co-authored 10 publications receiving 5590 citations. Previous affiliations of John R. Hampton include Cleveland Clinic.
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Journal ArticleDOI
An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction.
Maarten L. Simoons,Eric J. Topol,Robert M. Califf,Frans Van de Werf,Paul W. Armstrong,Philip Edmund Aylward,G.I. Barbash,Eric R. Bates,A. Betriu,James Chesebro,J Col,David de Bono,JM Gore,Alan Guerci,John R. Hampton +14 more
TL;DR: The findings of this large-scale trial indicate that accelerated t-PA given with intravenous heparin provides a survival benefit over previous standard thrombolytic regimens.
Journal ArticleDOI
Prophylactic Use of an Implantable Cardioverter-Defibrillator After Acute Myocardial Infarction
Stefan H. Hohnloser,Karl-Heinz Kuck,Paul Dorian,Robin S. Roberts,John R. Hampton,Robert Hatala,Eric Fain,Michael Gent,Stuart J. Connolly +8 more
TL;DR: Prophylactic ICD therapy does not reduce overall mortality in high-risk patients who have recently had a myocardial infarction, and is associated with a reduction in the rate of death due to arrhythmia, that was offset by an increase in the rates of death from nonarrhythmic causes.
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Significance of smoking in patients receiving thrombolytic therapy for acute myocardial infarction. Experience gleaned from the International Tissue Plasminogen Activator/Streptokinase Mortality Trial.
G I Barbash,Harvey D. White,Michaela Modan,Rafael Diaz,John R. Hampton,Juhani Heikkilä,A Kristinsson,S Moulopoulos,E A Paolasso,T. van der Werf +9 more
TL;DR: It is indicated that smokers receiving thrombolytic therapy after acute myocardial infarction have significantly better hospital and 6-month outcome than nonsmokers or ex-smokers and strenuous efforts should be made to decrease the incidence of new and continued smoking.
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After correcting for worse baseline characteristics, women treated with thrombolytic therapy for acute myocardial infarction have the same mortality and morbidity as men except for a higher incidence of hemorrhagic stroke. The Investigators of the International Tissue Plasminogen Activator/Streptokinase Mortality Study.
Harvey D. White,G I Barbash,Michaela Modan,John Simes,Rafael Diaz,John R. Hampton,Juhani Heikkilä,A Kristinsson,S Moulopoulos,E A Paolasso +9 more
TL;DR: After thrombolytic therapy for acute myocardial infarction, women have similar morbidity and mortality to men but suffer from a higher incidence of hemorrhagic stroke.
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Variations in Patient Management and Outcomes for Acute Myocardial Infarction in the United States and Other Countries: Results From the GUSTO Trial
Frans Van de Werf,Eric J. Topol,Kerry L. Lee,Lynn H. Woodlief,Christopher B. Granger,Paul W. Armstrong,Gabriel I. Barbash,John R. Hampton,Alan D. Guerci,R. John Simes,Allan M. Ross,Robert M. Califf +11 more
TL;DR: No significant evidence for a differentially greater benefit of accelerated rt-PA over streptokinase was found in US vs non-US patients, however, increased procedure and treatment use in the United States was associated with only a small decrease in short-term mortality.