Showing papers by "Eric Henderson published in 2005"

Method and apparatus for depositing material onto a surface

Abstract: Some embodiments of the present invention provide an apparatus and method in which material is deposited upon a surface from an elongated beam (102) having an aperture (104) defined therein through which the material is moved by passive adsorption. The elongated beam can be substantially planar along substantially its entire length, can be oriented at an acute angle with respect to the surface during deposition processes, and can have a length no greater than about 2mm. In some embodiments, the aperture can be elongated, can extend from a material reservoir (106) to a location short of the terminal end of the elongated beam or through the terminal end of the elongated beam, and can have a portion extending through the thickness of the elongated beam.

Microfluidic ultramicroscale deposition and patterning of quantum dots.

Abstract: The ability to directly deposit materials in ultraminiaturized domains with nanoscale accuracy could play a central role in the realization of some forms of nanotechnology. In this report we demonstrate the direct deposition of quantum dots in patterns with ultramicroscale (1-15 microm) and nanoscale (<1 microm) features. Unlike bottom up approaches that require preconfigured patterning steps, this top down 'direct write' method should be amenable to the construction of a large variety of patterns and features essentially 'on the fly'. To accomplish the direct writing/deposition of quantum dots we used a system that integrates high resolution motion control with microfabricated fluid delivery cartridges. This process is termed FEMTO (fluidics enhanced molecular transfer operation). The methodology demonstrated here may be extended to surface patterning and deposition of a broad spectrum of other nanoscale materials and thereby create opportunities in a variety of fields ranging from microelectronics to bio/nanotechnology.

Characterization of testudine melanomacrophage linear, membrane extension processes-cablepodia-by phase and atomic

Abstract: SUMMARY Melanomacrophages (MMs) are a component of an internal, pigmented cell system in liver and splenic tissues of some fishes, anurans, and reptiles. The cells have been found in centers or aggregates in sinusoids and are associated with cells capable of producing a peptide cytokine and immunoglobulins. A unique cell extension process has been observed in turtle MMs placed into cell culture, and this process has been studied by light and atomic force microscopy. These structures, referred to as cablepodia, are uniquely straight, narrow, and unbranching and appear to originate from growth cones opposite lamellipodia. Cablepodia were found to connect with other turtle MMs and fibroblasts forming cell networks. Dividing fibroblasts to which a cablepodium attached ceased cell division. The observations collectively suggest that a principal reason for aggregations of MMs in internal organs of lower vertebrates is their ability to form interconnected networks of cell processes for trapping and processing of particulate matter, cells, and infectious organisms and, possibly, for the communication of cell signals and transfer of intracellular materials.

Characterization of testudine melanomacrophage linear, membrane extension processes--cablepodia--by phase and atomic force microscopy.

Abstract: Melanomacrophages (MMs) are a component of an internal, pigmented cell system in liver and splenic tissues of some fishes, anurans, and reptiles. The cells have been found in centers or aggregates in sinusoids and are associated with cells capable of producing a peptide cytokine and immunoglobulins. A unique cell extension process has been observed in turtle MMs placed into cell culture, and this process has been studied by light and atomic force microscopy. These structures, referred to as cablepodia, are uniquely straight, narrow, and unbranching and appear to originate from growth cones opposite lamellipodia. Cablepodia were found to connect with other turtle MMs and fibroblasts forming cell networks. Dividing fibroblasts to which a cablepodium attached ceased cell division. The observations collectively suggest that a principal reason for aggregations of MMs in internal organs of lower vertebrates is their ability to form interconnected networks of cell processes for trapping and processing of particulate matter, cells, and infectious organisms and, possibly, for the communication of cell signals and transfer of intracellular materials.

Device and method of use for detection and characterization of microorganisms and microparticles

Abstract: The present invention includes a method and apparatus for the detection of a microorganism or microparticle.