E
Eric L. Chang
Researcher at University of Southern California
Publications - 325
Citations - 14740
Eric L. Chang is an academic researcher from University of Southern California. The author has contributed to research in topics: Radiosurgery & Radiation therapy. The author has an hindex of 53, co-authored 273 publications receiving 12599 citations. Previous affiliations of Eric L. Chang include LAC+USC Medical Center & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial.
Eric L. Chang,Jeffrey S. Wefel,Kenneth R. Hess,Pamela K. Allen,Frederick F. Lang,David G. Kornguth,Rebecca Arbuckle,J. Michael Swint,Almon S. Shiu,Moshe H. Maor,Christina A. Meyers +10 more
TL;DR: Patients treated with SRS plus WBRT were at a greater risk of a significant decline in learning and memory function by 4 months compared with the group that received SRS alone, and patients treatment with a combination of SRS and close clinical monitoring was recommended as the preferred treatment strategy.
Journal ArticleDOI
Palliative radiotherapy for bone metastases: an ASTRO evidence-based guideline.
Stephen Lutz,Lawrence Berk,Eric L. Chang,Edward Chow,Carol A. Hahn,Peter Hoskin,David R. Howell,Andre Konski,Lisa A. Kachnic,Simon S. Lo,Arjun Sahgal,Larry N. Silverman,Charles von Gunten,Ehud Mendel,Andrew D. Vassil,Deborah Watkins Bruner,William F. Hartsell +16 more
TL;DR: Radiotherapy is a successful and time efficient method by which to palliate pain and/or prevent the morbidity of bone metastases and is recommended for surgical decompression and postoperative radiotherapy in highly selected patients with sufficient performance status and life expectancy.
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Radiotherapeutic and surgical management for newly diagnosed brain metastasis(es): An American Society for Radiation Oncology evidence-based guideline
May N. Tsao,Dirk Rades,Andrew Wirth,Simon S. Lo,Brita Danielson,Laurie E. Gaspar,Paul W. Sperduto,Michael A. Vogelbaum,Jeffrey D. Radawski,Jian Z. Wang,Michael Gillin,Najeeb Mohideen,Carol A. Hahn,Eric L. Chang +13 more
TL;DR: Radiotherapeutic intervention (WBRT or radiosurgery) is associated with improved brain control and in selected patients with single brain metastasis, radiosur surgery or surgery has been found to improve survival and locally treated metastasis control.
Journal ArticleDOI
Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure
Eric L. Chang,Almon S. Shiu,Ehud Mendel,Leni A. Mathews,Anita Mahajan,Pamela K. Allen,Jeffrey S. Weinberg,Barry W. Brown,Xin Shelly Wang,Shiao Y. Woo,Charles S. Cleeland,Moshe H. Maor,Laurence D. Rhines +12 more
TL;DR: Analysis of the data obtained in the present study supports the safety and effectiveness of SBRT in cases of spinal metastatic cancer and considers it prudent to routinely treat the pedicles and posterior elements using a wide bone margin posterior to the diseased vertebrae because of the possible direct extension into these structures.
Journal ArticleDOI
International Spine Radiosurgery Consortium Consensus Guidelines for Target Volume Definition in Spinal Stereotactic Radiosurgery
Brett Cox,Daniel E. Spratt,Michael Lovelock,Mark H. Bilsky,Eric Lis,Samuel Ryu,Jason P. Sheehan,Peter C. Gerszten,Eric L. Chang,Iris C. Gibbs,Scott G. Soltys,Arjun Sahgal,Joseph O. Deasy,John C. Flickinger,Mubina Quader,Stefan A. Mindea,Yoshiya Yamada +16 more
TL;DR: Consensus recommendations include that the CTV should include abnormal marrow signal suspicious for microscopic invasion and an adjacent normal bony expansion to account for subclinical tumor spread in the marrow space.