E
Erika J. Martin
Researcher at Virginia Commonwealth University
Publications - 66
Citations - 1875
Erika J. Martin is an academic researcher from Virginia Commonwealth University. The author has contributed to research in topics: Platelet & Thrombin. The author has an hindex of 22, co-authored 66 publications receiving 1560 citations. Previous affiliations of Erika J. Martin include VCU Medical Center.
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Journal ArticleDOI
Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis
Alpha A. Fowler,Aamer Syed,Shelley Knowlson,Robin Sculthorpe,Don Farthing,Christine DeWilde,Christine A. Farthing,Terri Larus,Erika J. Martin,Donald F. Brophy,Seema Gupta,Bernard J. Fisher,Ramesh Natarajan +12 more
TL;DR: Intravenous ascorbic acid infusion was safe and well tolerated in this study and may positively impact the extent of multiple organ failure and biomarkers of inflammation and endothelial injury.
Journal ArticleDOI
Mechanisms of attenuation of abdominal sepsis induced acute lung injury by ascorbic acid
Bernard J. Fisher,Donatas Kraskauskas,Erika J. Martin,Daniela Farkas,Jacob A. Wegelin,Donald F. Brophy,Kevin R. Ward,Norbert F. Voelkel,Alpha A. Fowler,Ramesh Natarajan +9 more
TL;DR: Parenteral vitamin C infusion protected mice from the deleterious consequences of sepsis by multiple mechanisms, including attenuation of the proinflammatory response, enhancement of epithelial barrier function, increasing alveolar fluid clearance, and prevention of sePSis-associated coagulation abnormalities.
Journal ArticleDOI
Alterations of platelet aggregation kinetics with ultraviolet laser emission: the "stunned platelet" phenomenon.
On Topaz,Anthony J. Minisi,Nelson L. Bernardo,Richard A. McPherson,Erika J. Martin,Sheryl L. Carr,Marcus E. Carr +6 more
TL;DR: Aggregation kinetics are altered in platelets exposed to ultraviolet laser energy as manifested by decreased platelet aggregation and reduction in platelet force development capability, most pronounced at higher energy levels such as 60 mJ/mm2.
Journal ArticleDOI
Attenuation of Sepsis‐Induced Organ Injury in Mice by Vitamin C
Bernard J. Fisher,Donatas Kraskauskas,Erika J. Martin,Daniela Farkas,Puneet Puri,H. Davis Massey,Michael O. Idowu,Donald F. Brophy,Norbert F. Voelkel,Alpha A. Fowler,Ramesh Natarajan +10 more
TL;DR: VitC sufficiency or parenteral infusion of VitC, following induction of sepsis, normalized physiological functions that attenuated the development of MODS in sepsIs, and VitC deficient Gulo(-/-) mice were more susceptible to sepsic MODS.
Journal ArticleDOI
Coagulopathy and traumatic shock: characterizing hemostatic function during the critical period prior to fluid resuscitation.
TL;DR: Fibrinogen consumption and altered platelet function may account for the earliest changes in hemostatic function during traumatic shock.