Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

The Golden Age of Transfer Hydrogenation

Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous stream rather than in a flask Flow equipment provides chemists with unique control over reaction parameters enhancing reactivity or in some cases enabling new reactions This relatively young technology has received a remarkable amount of attention in the past decade with many reports on what can be done in flow Until recently, however, the question, “Should we do this in flow?” has merely been an afterthought This review introduces readers to the basic principles and fundamentals of flow chemistry and critically discusses recent flow chemistry accounts

The Hitchhiker's Guide to Flow Chemistry

Continuous-flow photochemistry in microreactors receives a lot of attention from researchers in academia and industry as this technology provides reduced reaction times, higher selectivities, straightforward scalability, and the possibility to safely use hazardous intermediates and gaseous reactants. In this review, an up-to-date overview is given of photochemical transformations in continuous-flow reactors, including applications in organic synthesis, material science, and water treatment. In addition, the advantages of continuous-flow photochemistry are pointed out and a thorough comparison with batch processing is presented.

Applications of Continuous-Flow Photochemistry in Organic Synthesis, Material Science, and Water Treatment

Bull. Chem. Soc. Jpn. への投稿のすすめ

Enantioselective organocatalytic synthesis of quaternary α-amino acids bearing a CF3 moiety.

In this review the recent progress in the field of self-optimizing reactor systems for continuous flow chemistry is presented. Particular focus is directed to the implementation of monitoring tools and realization of computer-controlled reaction optimizations without human interaction.

Online monitoring and analysis for autonomous continuous flow self-optimizing reactor systems

A new methodology for the immobilization of chiral Bronsted acids has been developed. The resulting heterogeneous organocatalysts have been employed in multiple consecutive catalysis cycles in the asymmetric organocatalytic transfer hydrogenation. The new catalyst system can not only be easily recovered from the reaction mixture in a tea-bag approach but it can also be easily reused in several catalytic cycles without loss of reactivity and selectivity.

Erli Sugiono

Papers

Complete Field Guide to Asymmetric BINOL-Phosphate Derived Brønsted Acid and Metal Catalysis: History and Classification by Mode of Activation; Brønsted Acidity, Hydrogen Bonding, Ion Pairing, and Metal Phosphates

Enantioselective organocatalytic synthesis of quaternary α-amino acids bearing a CF3 moiety.

Online monitoring and analysis for autonomous continuous flow self-optimizing reactor systems

Synthesis and Application of Polymer-Supported Chiral Brønsted Acid Organocatalysts

Brønsted Acid Catalysis: Hydrogen Bonding versus Ion Pairing in Imine Activation