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Erzhen Chen
Researcher at Shanghai Jiao Tong University
Publications - 37
Citations - 1219
Erzhen Chen is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 4 publications receiving 860 citations.
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Journal ArticleDOI
Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial.
Wei Tang,Zhujun Cao,Mingfeng Han,Zhengyan Wang,Junwen Chen,Wenjin Sun,Yaojie Wu,Wei Xiao,Shengyong Liu,Erzhen Chen,Wei Chen,Xiongbiao Wang,Jiuyong Yang,Jun Lin,Qingxia Zhao,Youqin Yan,Zhibin Xie,Dan Li,Yaofeng Yang,Leshan Liu,Jieming Qu,Guang Ning,Guochao Shi,Qing Xie +23 more
TL;DR: Administration of hydroxychloroquine did not result in a significantly higher probability of negative conversion than standard of care alone in patients admitted to hospital with mainly persistent mild to moderate covid-19, and adverse events were higher in hydroxy chloroquine recipients than in non-recipients.
Posted ContentDOI
Hydroxychloroquine in patients mainly with mild to moderate COVID–19: an open–label, randomized, controlled trial
Wei Tang,Zhujun Cao,Mingfeng Han,Zhengyan Wang,Junwen Chen,Wenjin Sun,Yaojie Wu,Wei Xiao,Shengyong Liu,Erzhen Chen,Wei Chen,Xiongbiao Wang,Jiuyong Yang,Jun Lin,Qingxia Zhao,Youqin Yan,Zhibin Xie,Dan Li,Yaofeng Yang,Leshan Liu,Jieming Qu,Guang Ning,Guochao Shi,Qing Xie +23 more
TL;DR: The administration of HCQ did not result in a higher negative conversion rate but more alleviation of clinical symptoms than SOC alone in patients hospitalized with COVID-19 without receiving antiviral treatment, possibly through anti-inflammatory effects.
Journal ArticleDOI
Reduced sensitivity of SARS-CoV-2 Omicron variant to antibody neutralization elicited by booster vaccination
Xiaoqi Yu,Dong Wei,Wenxin Xu,Yulong Li,Xinxin Li,Xinxin Zhang,Jie-Ming Qu,Zhi-Tao Yang,Erzhen Chen +8 more
TL;DR: A homologous booster dose of the BBIBP-CorV vaccine was administered to eligible healthcare workers in Shanghai Ruijin Hospital to investigate whether the newly identified Omicron variant can escape serum antibody neutralization induced by the booster vaccination.
Journal ArticleDOI
Reduced sensitivity of SARS-CoV-2 Omicron variant to antibody neutralization elicited by booster vaccination
Journal ArticleDOI
Neutralizing activity of BBIBP-CorV vaccine-elicited sera against Beta, Delta and other SARS-CoV-2 variants of concern
Xiaoqi Yu,Dong Wei,Wenxin Xu,Chuanmiao Liu,Wentian Guo,Xinxin Li,Wei Tan,Leshan Liu,Xinxin Zhang,Jie-Ming Qu,Zhi-Tao Yang,Erzhen Chen +11 more
TL;DR: In this paper , the safety and immunogenicity of the inactivated SARS-CoV-2 vaccine BBIBP-CorV were evaluated in a cohort of 1006 vaccine recipients.