E
Esper G. Kallas
Researcher at University of São Paulo
Publications - 291
Citations - 15157
Esper G. Kallas is an academic researcher from University of São Paulo. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 51, co-authored 255 publications receiving 12763 citations. Previous affiliations of Esper G. Kallas include University of Rochester & Global Virus Network.
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Journal ArticleDOI
Comprehensive Antiretroviral Restriction Factor Profiling Reveals the Evolutionary Imprint of the ex Vivo and in Vivo IFN-β Response in HTLV-1-Associated Neuroinflammation.
Fabio E. Leal,Soraya Maria Menezes,Emanuela Avelar Silva Costa,Phillip M. Brailey,Lucio Gama,Aluísio Augusto Cotrim Segurado,Esper G. Kallas,Douglas F. Nixon,Tim Dierckx,Ricardo Khouri,Ricardo Khouri,Jurgen Vercauteren,Bernardo Galvão-Castro,Rui André Saraiva Raposo,Johan Van Weyenbergh +14 more
TL;DR: Ex vivo mechanistic evidence is provided for the observed immunovirological effect of in vivo IFN-β treatment in HAM/TSP, reconcile an apparent IFN paradox in HTLV-1 research and identify biomarkers/targets for a precision medicine approach.
Journal ArticleDOI
Syndemics among individuals enrolled in the PrEP Brasil Study
Raquel Brandini De Boni,Iona K. Machado,Mauricio Teixeira Leite de Vasconcellos,Brenda Hoagland,Esper G. Kallas,José Valdez Madruga,Nilo Martinez Fernandes,Natalia B. Cerqueira,Ronaldo I. Moreira,Silvia Goulart,Valdilea G. Veloso,Beatriz Grinsztejn,Paula M. Luz +12 more
TL;DR: Given the high prevalence of syndemics, particularly of polysubstance use and binge drinking, PrEP delivery offers an opportunity to diagnose and intervene in mental and social well-being.
Journal ArticleDOI
Short communication: HIV type 1 subtype BF leads to faster CD4+ T cell loss compared to subtype B.
Leandro F. Tarosso,Sabri Saeed Sanabani,Susan Pereira Ribeiro,Mariana M. Sauer,Helena Tomiyama,Maria Cecília Araripe Sucupira,Ricardo Sobhie Diaz,Ester Cerdeira Sabino,Jorge Kalil,Esper G. Kallas +9 more
TL;DR: In this paper, a longitudinal analysis revealed that subtype BF was associated with a faster CD4+ T cell decline compared to infection with subtype B, in spite of a similar plasma HIV-1 load.
Journal ArticleDOI
Unexpected diversity of cellular immune responses against Nef and Vif in HIV-1-infected patients who spontaneously control viral replication.
Leandro F. Tarosso,Mariana M. Sauer,Sabri Saeed Sanabani,Maria Teresa M. Giret,Helena Tomiyama,John Sidney,Shari M. Piaskowski,Ricardo Sobhie Diaz,Ester Cerdeira Sabino,Alessandro Sette,Jorge Kalil-Filho,David I. Watkins,Esper G. Kallas,Esper G. Kallas +13 more
TL;DR: Interestingly, three of the authors' patients had broader cellular immune responses against HLA class I-predicted minimal optimal epitopes from either autologous viruses or from the HIV-1 consensus B sequence, when compared to responses against the 15-mer HIV- 1 type B consensus peptides.
Journal ArticleDOI
Lack of evidence to support the association of a single IL28B genotype SNP rs12979860 with the HTLV-1 clinical outcomes and proviral load
Sabri Saeed Sanabani,Youko Nukui,Juliana Pereira,Antonio Charlys da Costa,Ana Carolina Soares de Oliveira,Rodrigo Pessôa,Fabio E. Leal,Aluísio Augusto Cotrim Segurado,Esper G. Kallas,Ester Cerdeira Sabino +9 more
TL;DR: This study failed to support the previously reported positive association between the IL28B rs12979860 polymorphisms and an increased risk of developing HAM/TSP in the Brazilian population.