E
Estrella Soria
Researcher at Carlos III Health Institute
Publications - 4
Citations - 357
Estrella Soria is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Akt/PKB signaling pathway & ASK1. The author has an hindex of 4, co-authored 4 publications receiving 341 citations.
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Journal ArticleDOI
Involvement of Rho GTPases in the Transcriptional Inhibition of Preproendothelin-1 Gene Expression by Simvastatin in Vascular Endothelial Cells
TL;DR: The basal transcription rate of the preproendothelin-1 gene was decreased by simvastatin in bovine aortic endothelial cells and the Rho proteins play an essential role in the control of vascular tone and proliferative response.
Journal ArticleDOI
Activation of the mitogen activated protein kinase extracellular signal-regulated kinase 1 and 2 by the nitric oxide-cGMP-cGMP-dependent protein kinase axis regulates the expression of matrix metalloproteinase 13 in vascular endothelial cells.
Carlos Zaragoza,Estrella Soria,Esther López,Darren D Browning,Milagros Balbín,Carlos López-Otín,Santiago Lamas +6 more
TL;DR: It is proposed that the NO-cGMP-PKG pathway enhances MMP-13 expression by the activation of ERK 1,2, and may be important in the context of pathophysiological conditions such as inflammation or atherogenesis.
Journal ArticleDOI
Inactivation of Foxo3a and Subsequent Downregulation of PGC-1α Mediate Nitric Oxide-Induced Endothelial Cell Migration
Sara Borniquel,Nieves García-Quintáns,Inmaculada Valle,Yolanda Olmos,Brigitte Wild,Francisco Martínez-Granero,Estrella Soria,Santiago Lamas,María Monsalve +8 more
TL;DR: Results show that NO-mediated downregulation of PGC-1α is necessary for NO-induced endothelial migration and that the ROS detoxification system in endothelial cells are mediated by the PI3K/Akt signaling pathway and subsequent inactivation of the FoxO transcription factor Foxo3a.
Journal Article
Erratum: Activation of the mitogen activated protein kinase extracellular signal-regulated kinase 1 and 2 by the nitric oxide-cGMP-cGMP-dependent protein kinase axis regulates the expression of matrix metalloproteinase 13 in vascular endothelial cells (Molecular Pharmacology (2002) 62 (927-935))
Carlos Zaragoza,Estrella Soria,E. López,Darren D Browning,Milagros Balbín,Carlos López-Otín,Santiago Lamas +6 more