É
Éva Margittai
Researcher at Semmelweis University
Publications - 37
Citations - 7128
Éva Margittai is an academic researcher from Semmelweis University. The author has contributed to research in topics: Endoplasmic reticulum & Unfolded protein response. The author has an hindex of 20, co-authored 37 publications receiving 6459 citations. Previous affiliations of Éva Margittai include Hungarian Academy of Sciences & Vita-Salute San Raffaele University.
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Journal ArticleDOI
Arterial Tortuosity Syndrome: An Ascorbate Compartmentalization Disorder?
Annekatrien Boel,Krisztina Veszelyi,Csilla E. Németh,Aude Beyens,Andy Willaert,Paul Coucke,Bert Callewaert,Éva Margittai +7 more
TL;DR: The current knowledge on ATS and the role of GLUT10 within the compartmentalization of ascorbate in physiological and diseased states is revised.
Journal ArticleDOI
The glucose-6-phosphate transport is not mediated by a glucose-6-phosphate/phosphate exchange in liver microsomes
Paola Marcolongo,Rosella Fulceri,Roberta Giunti,Éva Margittai,Gábor Bánhegyi,Angelo Benedetti +5 more
TL;DR: It is concluded that hepatic G6PT functions as an uniporter in rat liver microsomal vesicles, similar to other glucose‐6‐phosphate transporter proteins described in liposomes including the reconstituded transporter protein.
Journal ArticleDOI
Decreased Nuclear Ascorbate Accumulation Accompanied with Altered Genomic Methylation Pattern in Fibroblasts from Arterial Tortuosity Syndrome Patients.
Csilla E. Németh,Zsofia Nemoda,Péter Lőw,Pál Szabó,Erzsébet Horváth,Andy Willaert,Annekatrien Boel,Bert Callewaert,Paul Coucke,Marina Colombi,Gábor Bánhegyi,Gábor Bánhegyi,Éva Margittai +12 more
TL;DR: The altered DNA hydroxymethylation patterns in patient cells both at the global level and at specific gene regions accompanied with decreased nuclear accumulation of ascorbate suggests the epigenetic role of vitamin C in the pathomechanism of ATS.
Journal ArticleDOI
Different expression and distribution of 11β-hydroxysteroid dehydrogenase type 1 in obese and lean animal models of type 2 diabetes (Short communication)
TL;DR: The results suggest that the prereceptorial glucocorticoid activation is different in the liver and adipose tissue of the two diabetes models, which might be responsible for the obese and lean phenotypes in type 2 diabetes.
Posted ContentDOI
Mevalonate pathway-mediated ER homeostasis is required for haploid stability in human somatic cells
TL;DR: The data demonstrate the involvement of the mevalonate pathway in the stability of the haploid state in human somatic cells through managing ER stress, highlighting a novel link between ploidy and ER homeostatic control.