E
Eva Nicksch
Researcher at Max Planck Society
Publications - 1
Citations - 942
Eva Nicksch is an academic researcher from Max Planck Society. The author has contributed to research in topics: Oligodendrocyte & Myelin. The author has an hindex of 1, co-authored 1 publications receiving 868 citations.
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Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination
Corinna Lappe-Siefke,Sandra Goebbels,Michel Gravel,Eva Nicksch,John H.S. Lee,Peter E. Braun,Ian R. Griffiths,Klaus-Armin Nave +7 more
TL;DR: It is shown that Cnp1, which encodes 2′,3′-cyclic nucleotide phosphodiesterase in oligodendrocytes, is essential for axonal survival but not for myelin assembly, and the chief function of glia in supporting axonal integrity can thus be completely uncoupled from its function in maintaining compact myelin.