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Fang Chen

Researcher at Sichuan University

Publications -  149
Citations -  2612

Fang Chen is an academic researcher from Sichuan University. The author has contributed to research in topics: Jatropha curcas & Gene. The author has an hindex of 26, co-authored 139 publications receiving 2148 citations. Previous affiliations of Fang Chen include Chinese Ministry of Education.

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Journal Article

Antitumor effects of curcin from seeds of Jatropha curcas.

TL;DR: Curcin has an obvious antitumor effect and its mechanisms are related to the N-glycosidase activity, and there were relatively high similarities among them.
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Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells

TL;DR: The results demonstrated that 6-OHDA-induced ferroptosis could be observed in vivo zebrafish and in vitro human dopaminergic cell line (SH-SY5Y cells) model and found that high p62/SQSTM1 (p62) expression could protect SH-SY 5Y cells against ferroPTosis through promoting Nrf2 nuclear transfer and upregulating the expression of the antioxidant protein heme oxygenase-1 (HO-1).
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A novel betaine aldehyde dehydrogenase gene from Jatropha curcas, encoding an enzyme implicated in adaptation to environmental stress

TL;DR: In this paper, a novel betaine aldehyde dehydrogenase gene, named JcBD1, was cloned by RT-PCR and RACE techniques from Jatropha curcas L., an important plant species as its seed is the raw material for biodiesels.
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Growth and antioxidant responses in Jatropha curcas seedling exposed to mercury toxicity.

TL;DR: It is shown that mercury is readily accumulated by germinating embryos and growing seedlings, and its content was greater in the radicles than those of in the cotyledons and hypocotyls, and analysis of superoxide dismutase, peroxidase and catalase isoenzymes suggested that different patterns depend on mercury concentrations and tissue types.
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A novel sialic acid-specific lectin from Phaseolus coccineus seeds with potent antineoplastic and antifungal activities.

TL;DR: A novel lectin with specificity towards sialic acid was purified from Phaseolus coccineus L. multiflorus willd seeds and showed remarkable antifungal activity towards some plant pathogenic fungi and a significant correlation between sIALic acid-specific site and its bi-functional bioactivities is suggested.